Fig 4

Repeat structure of the REP23 containing gene yahH (the same as X002) and its protein YahH [58]. The upper part shows one repeat block folded as mRNA [59]. The DNA sequence (lower part) basically consists of five of such repeated blocks, with only minor differences (when compared to each other – single nt differences are in green) and a short unique sequence at the 3’-end (green stretch). When comparing the fourth block to the other, a base appears to be missing (red marked gap) causing a change in the reading frame visible in the protein structure. Thus, the protein contains three large repeats and a fourth truncated one (grey blocks, few differences in aa indicated in blue). Downstream of the “frame shift” mutation, a different structure of two blocks is found (yellow). The protein contains many charged amino acids, either positive (RK, red print) or negative (DE, blue print)