Fig. 4

Isoform expression and gene structure of PRICKLE1. a Expression pattern of PRICKLE1 isoforms uc010skw.1 and uc001rnl.2. Two expression patterns (red and black) were identified by K-means clustering in subsets of breast samples. b PRICKLE1 gene structure.uc001skw.1 and uc001rnl.2 contain alternative 3’ splice site in exon 7 (red). c 5’ UTR structure of PRICKLE1 and putative RNA binding proteins. Alternative 3’ splice site (red) and hairpin structure at the flanking region (blue) are enriched with putative binding sites of RNA binding proteins