Fig. 1
From: Self-regulation of functional pathways by motifs inside the disordered tails of beta-catenin
Predicted intrinsic disorder of and predicted binding motifs in human beta-Catenin (UniProtKB Entry: P35222). X-axis shows sequential indexes of amino acids. Y-axis displays disorder scores predicted by PONDR-FIT (upper panel) and PONDR©VLXT (lower panel). Residues with score higher than 0.5 are disordered, otherwise structured. In addition, residues with score between ~0.3 and 0.5 are assumed to be flexible, and residues with score close to zero are extremely rigid. The gray shadow behind PONDR-FIT prediction is the estimated prediction error from PONDR-FIT predictor. Horizontal blue bars in the upper panel represent the domain structure of twelve armadillo repeats. Dark cyan bars in the middle of lower panel are helices predicted by NetSurP. Binding motifs were predicted by MoRF (dark yellow), ANCHOR (brown), and MoRFpred (dark green) predictors, respectively. The 3D structure for the armadillo domain of human beta-Catenin (PDB id: 1JDH) was placed on the top of the figure