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Table 2 Shows the medians of the sequence features and the p-values between the Alz proteins and NonAlz proteins sets

From: Integrating network, sequence and functional features using machine learning approaches towards identification of novel Alzheimer genes

Sequence feature

Alz genes

NonAlz genes

p-value

Molecular weight

54349.54

49547.60

1.61E-02

Residues

491

443

1.49E-02

Average residue weight

111.83

111.90

3.09E-01

Charge

1

4

1.64E-07

Isoelectric Point

6.60

7.22

3.06E-08

A280 Molar Extinction Coefficients

50880

44380

7.66E-05

A = Ala

6.81

6.85

7.98E-01

F = Phe

3.77

3.56

1.48E-02

L = Leu

9.38

9.81

2.01E-02

N = Asn

3.78

3.46

1.22E-04

P = Pro

5.33

5.52

5.42E-02

R = Arg

5.09

5.55

4.89E-06

S = Ser

7.53

7.59

2.97E-01

T = Thr

5.31

5.04

6.63E-04

Aliphatic

27.7

27.6

6.34E-01

Polar

47.0

47.2

5.28E-01

Non-polar

52.9

52.7

5.28E-01

Small

50

49.3

3.80E-02

Basic

13.46

13.99

1.82E-04

Aromatic

10.63

10.15

4.97E-02

Acidic

11.94

11.73

3.64E-02