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Fig. 5 | BMC Genomics

Fig. 5

From: Dhurrin metabolism in the developing grain of Sorghum bicolor (L.) Moench investigated by metabolite profiling and novel clustering analyses of time-resolved transcriptomic data

Fig. 5

Expression profiles linked to the biosynthetic- and bioactivation pathway. The biosynthetic pathway involves the enzymes CYP79A1, CYP71E1 and UGT85B1 with the formation of dhurrin from L-tyrosine. The bioactivation pathway hydrolyzes dhurrin to release HCN via the enzymes DHR1 and 2 and HNL. The detoxification pathway converts the HCN to aspartate + NH3 and/or asparagine via CAS and the NIT4A/B1 and NIT4A/B2 heterodimers. The expression profiles for the specific enzyme involved in the reactions in the biosynthetic- or bioactivation pathway are colored in the same color as the enzyme boxes. In the box representing the POR expression, the a, b and c represents the three different isoforms found in sorghum. Expression is displayed in fragments per kilobase of exon per million reads mapped (FPKM). The dashed line in each transcription box represents the dhurrin concentration throughout development

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