From: Conserved gene expression in sperm reservoirs between birds and mammals in response to mating
GO-BP (immune function) | REF | DE (775) | EXPC | FE (+/−) | P value |
---|---|---|---|---|---|
Positive regulation of antigen processing and presentation of peptide antigen via MHC class II (GO:0002588) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002582) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Cytokine secretion involved in immune response (GO:0002374) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
B cell cytokine production (GO:0002368) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Positive regulation of IP-10 production (GO:0071660) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Regulation of IP-10 production (GO:0071658) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Positive regulation of B cell chemotaxis (GO:2000538) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Regulation of B cell chemotaxis (GO:2000537) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway (GO:0038097) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Tumor necrosis factor secretion (GO:1990774) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Isotype switching to IgG isotypes (GO:0048291) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
T-helper 1 cell activation (GO:0035711) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Response to TNF agonist (GO:0061481) | 1 | 1 | 0.04 | +27.61 | 3.56E-02 |
Positive regulation of interleukin-1 alpha secretion (GO:0050717) | 3 | 2 | 0.11 | +18.41 | 5.49E-03 |
regulation of T cell mediated immune response to tumor cell (GO:0002840) | 3 | 2 | 0.11 | +18.41 | 5.49E-03 |
Positive regulation of interleukin-1 alpha production (GO:0032730) | 4 | 2 | 0.14 | +13.81 | 9.52E-03 |
Regulation of interleukin-1 alpha secretion (GO:0050705) | 4 | 2 | 0.14 | +13.81 | 9.52E-03 |
Toll-like receptor 2 signaling pathway (GO:0034134) | 5 | 2 | 0.18 | +11.04 | 1.45E-02 |
Regulation of interleukin-1 alpha production (GO:0032650) | 5 | 2 | 0.18 | +11.04 | 1.45E-02 |
Interleukin-10 production (GO:0032613) | 5 | 2 | 0.18 | +11.04 | 1.45E-02 |
Positive regulation of interleukin-1 secretion (GO:0050716) | 11 | 4 | 0.4 | +10.04 | 7.60E-04 |
Regulation of type I interferon-mediated signaling pathway (GO:0060338) | 13 | 4 | 0.47 | +8.5 | 1.40E-03 |
Positive regulation of interleukin-1 beta secretion (GO:0050718) | 10 | 3 | 0.36 | +8.28 | 6.03E-03 |
Positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 7 | 2 | 0.25 | +7.89 | 2.72E-02 |
Positive regulation of interleukin-1 production (GO:0032732) | 14 | 4 | 0.51 | +7.89 | 1.83E-03 |
Interleukin-8 production (GO:0032637) | 7 | 2 | 0.25 | +7.89 | 2.72E-02 |
Regulation of interleukin-1 beta secretion (GO:0050706) | 14 | 4 | 0.51 | +7.89 | 1.83E-03 |
Regulation of interleukin-1 secretion (GO:0050704) | 18 | 5 | 0.65 | +7.67 | 5.67E-04 |
Positive regulation of interleukin-10 production (GO:0032733) | 19 | 5 | 0.69 | +7.27 | 7.21E-04 |
Positive regulation of interleukin-8 secretion (GO:2000484) | 8 | 2 | 0.29 | +6.9 | 3.47E-02 |
Positive regulation of interleukin-1 beta production (GO:0032731) | 12 | 3 | 0.43 | +6.9 | 9.89E-03 |
Positive regulation of interferon-alpha production (GO:0032727) | 12 | 3 | 0.43 | +6.9 | 9.89E-03 |
Toll-like receptor 4 signaling pathway (GO:0034142) | 13 | 3 | 0.47 | +6.37 | 1.22E-02 |
Positive regulation of interleukin-6 secretion (GO:2000778) | 13 | 3 | 0.47 | +6.37 | 1.22E-02 |
Regulation of response to interferon-gamma (GO:0060330) | 9 | 2 | 0.33 | +6.14 | 4.28E-02 |
Inflammatory response to antigenic stimulus (GO:0002437) | 14 | 3 | 0.51 | +5.92 | 1.49E-02 |
Regulation of interferon-alpha production (GO:0032647) | 14 | 3 | 0.51 | +5.92 | 1.49E-02 |
Regulation of interleukin-10 production (GO:0032653) | 26 | 5 | 0.94 | +5.31 | 2.82E-03 |
Regulation of interleukin-1 beta production (GO:0032651) | 27 | 5 | 0.98 | +5.11 | 3.30E-03 |
Regulation of interleukin-1 production (GO:0032652) | 34 | 6 | 1.23 | +4.87 | 1.69E-03 |
MyD88-dependent toll-like receptor signaling pathway (GO:0002755) | 17 | 3 | 0.62 | +4.87 | 2.46E-02 |
Cellular response to interleukin-4 (GO:0071353) | 18 | 3 | 0.65 | +4.6 | 2.85E-02 |
Positive regulation of interferon-beta production (GO:0032728) | 20 | 3 | 0.72 | +4.14 | 3.71E-02 |
Positive regulation of type I interferon production (GO:0032481) | 27 | 4 | 0.98 | +4.09 | 1.76E-02 |
Somatic diversification of immune receptors via germline recombination within a single locus (GO:0002562) | 28 | 4 | 1.01 | +3.94 | 1.98E-02 |
Positive regulation of interleukin-6 production (GO:0032755) | 42 | 6 | 1.52 | +3.94 | 4.71E-03 |
Positive regulation of interleukin-8 production (GO:0032757) | 30 | 4 | 1.09 | +3.68 | 2.47E-02 |
Regulation of interferon-beta production (GO:0032648) | 30 | 4 | 1.09 | +3.68 | 2.47E-02 |
Regulation of type I interferon production (GO:0032479) | 38 | 5 | 1.38 | +3.63 | 1.33E-02 |
Toll-like receptor signaling pathway (GO:0002224) | 40 | 5 | 1.45 | +3.45 | 1.62E-02 |
Positive regulation of tumor necrosis factor production (GO:0032760) | 34 | 4 | 1.23 | +3.25 | 3.64E-02 |
Positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 35 | 4 | 1.27 | +3.16 | 3.98E-02 |
Positive regulation of cytokine secretion (GO:0050715) | 62 | 7 | 2.25 | +3.12 | 8.19E-03 |
Positive regulation of innate immune response (GO:0045089) | 90 | 10 | 3.26 | +3.07 | 1.96E-03 |
Positive regulation of adaptive immune response (GO:0002821) | 57 | 6 | 2.06 | +2.91 | 1.88E-02 |
Regulation of cytokine-mediated signaling pathway (GO:0001959) | 60 | 6 | 2.17 | +2.76 | 2.35E-02 |
Regulation of interleukin-6 production (GO:0032675) | 70 | 7 | 2.54 | +2.76 | 1.50E-02 |
Regulation of response to cytokine stimulus (GO:0060759) | 62 | 6 | 2.25 | +2.67 | 2.69E-02 |
Positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002824) | 54 | 5 | 1.96 | +2.56 | 4.85E-02 |
Regulation of innate immune response (GO:0045088) | 154 | 14 | 5.58 | +2.51 | 1.83E-03 |
Regulation of lymphocyte mediated immunity (GO:0002706) | 82 | 7 | 2.97 | +2.36 | 3.17E-02 |
Positive regulation of defense response (GO:0031349) | 155 | 11 | 5.61 | +1.96 | 2.82E-02 |
Regulation of immune effector process (GO:0002697) | 260 | 18 | 9.42 | +1.91 | 7.84E-03 |
Positive regulation of immune response (GO:0050778) | 256 | 17 | 9.27 | +1.83 | 1.39E-02 |
Regulation of inflammatory response (GO:0050727) | 185 | 12 | 6.7 | +1.79 | 4.03E-02 |
Regulation of leukocyte cell-cell adhesion (GO:1903037) | 189 | 12 | 6.85 | +1.75 | 4.59E-02 |
Regulation of defense response (GO:0031347) | 394 | 25 | 14.27 | +1.75 | 5.84E-03 |
Immune effector process (GO:0002252) | 253 | 16 | 9.16 | +1.75 | 2.46E-02 |
Regulation of immune response (GO:0050776) | 398 | 25 | 14.41 | +1.73 | 6.59E-03 |
Regulation of cytokine production (GO:0001817) | 352 | 22 | 12.75 | +1.73 | 1.09E-02 |
Innate immune response (GO:0045087) | 280 | 17 | 10.14 | +1.68 | 2.93E-02 |
Positive regulation of immune system process (GO:0002684) | 481 | 29 | 17.42 | +1.66 | 6.26E-03 |
Immune system development (GO:0002520) | 470 | 28 | 17.02 | +1.64 | 8.28E-03 |
Regulation of immune system process (GO:0002682) | 785 | 45 | 28.43 | +1.58 | 2.05E-03 |
Cytokine-mediated signaling pathway (GO:0019221) | 295 | 4 | 10.68 | - 0.37 | 1.81E-02 |