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Table 1 Effects on precision and recall for D2.2.301H and D2.2.302H before and following removal of proteins with heavy loadings on the first principal component (PC1 and − PC1 respectively)

From: Protein complex-based analysis is resistant to the obfuscating consequences of batch effects --- a case study in clinical proteomics

 

Precision

Recall

F-score

Jaccard

301H (PC1)

1.00

0.30

0.46

 

301H (-PC1)

1.00

0.35

0.52

 

301H (TT/-PC1)

0.65

0.23

0.34

0.48

302H (PC1)

0.94

0.32

0.48

 

302H (-PC1)

0.93

0.43

0.59

 

302H (TT/-PC1)

0.72

0.30

0.42

0.61

  1. TT refers to the standard t-test while TT/-PC1 are the top n-ranked TT-features (restricted to the number of features in –PC1). The Jaccard coefficient indicates limited overlaps amongst the top TT-features associated with –PC1 features