Table 2 Classification of some important multigene families in CMB-1 isolate
Protein class description | No. of genes | SNPs per gene | Average SNPs per base (%) |
|---|---|---|---|
reticulocyte binding protein (PvRBP) | 6 | 70.50 | 0.99 |
Merozoite surface protein 3 (MSP3) | 11 | 55.91 | 1.96 |
serine-repeat antigen (SERA) | 13 | 45.46 | 1.53 |
variable surface protein (VIR) | 115 | 30.61 | 1.92 |
transcription factor with AP2 | 27 | 20.93 | 0.34 |
protein kinase | 20 | 18.15 | 0.36 |
Merozoite surface protein 7 (MSP7) | 11 | 16.18 | 1.46 |
Pv-fam-d | 12 | 12.50 | 0.64 |
DNA-directed RPB | 15 | 10.07 | 0.36 |
PST-A | 6 | 9.17 | 0.56 |
Phist protein (Pf-fam-b) | 22 | 8.73 | 0.66 |
DnaJ | 14 | 8.43 | 0.53 |
serine/threonine kinase | 25 | 7.76 | 0.24 |
RAD protein (Pv-fam-e) | 39 | 7.13 | 0.80 |
tryptophan-rich antigen (Pv-fam-a) | 19 | 6.63 | 0.38 |
6-cysteine | 13 | 6.15 | 0.25 |
all genes in whole genome | 5626 | 5.97 | 0.15 |