Table 2 Eighteen mRNAs^a with greatest pleiotropy across metabolic traits using a cut-off of FDR <0.001 to define significance of association

FAM13A

family with sequence similarity 13, member A

6

All

CSF2RB

colony stimulating factor 2 receptor, beta, low-affinity

6

All

HIST1H2AC

histone cluster 1, H2ac

6

All

WNK1

WNK lysine deficient protein kinase 1

6

All

ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

5

All but glucose

LSP1

lymphocyte-specific protein 1

5

All but glucose

LMBRD1

LMBR1 domain containing 1

5

All but SBP

ZNF721

zinc finger protein 721

5

All but SBP

PARP15

poly (ADP-ribose) polymerase family, member 15

5

All but glucose

ZNF644

zinc finger protein 644

5

All but SBP

AP2B1

adaptor-related protein complex 2, beta 1 subunit

5

All but SBP

PDS5B

PDS5, regulator of cohesion maintenance, homolog B

5

All but glucose

HIST1H4E

histone cluster 1, H4e

5

All but HDL-C

ZNF267

zinc finger protein 267

5

All but HDL-C

SAMHD1

SAM domain and HD domain 1

5

All but HDL-C

CAPN2

calpain 2, (m/II) large subunit

5

All but HDL-C

KLF10

Kruppel-like factor 10

5

All but HDL-C

CAST

calpastatin

5

All but HDL-C