Fig. 4From: Mechanisms of Groucho-mediated repression revealed by genome-wide analysis of Groucho binding and activityGroucho is recruited to both VRRs and VARs. a Genome browser views showing Gro ChIP-seq signal in genomic regions containing the two Dorsal repression targets zen and dpp. The positions of Dorsal binding site-containing VRRs in each gene are indicated. b Genome browser views showing Gro ChIP-seq signal in genomic regions containing the two Dorsal activation targets sna and rho. Dorsal binds and activates sna through a primary enhancer and a secondary (shadow) enhancer [65, 66]. Dorsal binds and activates rho through its neuroectodermal enhancer (nee). c Dorsal binds with high frequency to all three classes of Dorsal binding sites. Sites are categorized as described previously [69]. See text for a discussion of the roles of the three types of sitesBack to article page