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Fig. 3 | BMC Genomics

Fig. 3

From: Sex differences in the molecular signature of the developing mouse hippocampus

Fig. 3

Changes in expression through discrete periods of postnatal development. a & b: GO enrichment treemap for transcripts upregulated between 1 and 2 months, and 2 and 4 months respectively. c: shotgun plot for comparison of 1 and 2 month old animals. The log transformed fold change for each gene is plotted along the y axis, and the mean read count value is plotted along the x axis. Log2 fold changes were calculated by taking the log (base2) of the quotient of mean counts in relatively older animals (numerator) and relatively younger animals (denominator). Transcripts with more numerous read counts appear further to the right. Red points are genes that are up or down-regulated significantly (q < 0.05). d: Venn diagram comparing genes DE between 1 and 2 month, and 2 and 4 months of age. e: shotgun plot for comparison of 2 and 4 month old animals. 3f & 3g): GO enrichment treemap for transcripts down-regulated between 1 and 2 month and 2 and 4 months respectively. For c and e the number of total differentially expressed transcripts is shown in the upper right corner and the number of up-regulated vs down-regulated transcripts is shown with an up or down arrow

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