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Fig. 1 | BMC Genomics

Fig. 1

From: Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo

Fig. 1

Design of MeDIP-array for previously LTP associated genes. a Genes identified as differentially expressed in Maag et al. 2015, with an absolute logFC ≥ 0.9 and FDR ≤ 0.05, were targeted in this array. Briefly, probes were designed around an area of 3 kb of the TSS and CpG islands associated with these genes. The intensity of each probe was calculated using limma. In total, 38,119 probes were created for this experiment. b Each probe was collapsed into their specific group based on their location near their associated gene. Probes could be located in promoters, CpG-islands, shore, or a combination of all the previous elements. The majority of probes fell into the shores region

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