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Fig. 5 | BMC Genomics

Fig. 5

From: Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo

Fig. 5

Chromatin marks show enrichment over correlated genes in normal rat brain. Public ChIP-seq control data sets were downloaded and analysed over the correlated and non-correlated genes with the respect of their (a) TSS ± 3 kb or (b) the whole gene body ± 3 kb from TSS and TES. H3K27ac, H2K4me2, H3K4me1, and Matrin 3 was obtained from a growth hormone (GH)- expressing rat pituitary cell line [49]), H3K9me3 from rat hippocampal tissue [50], PolII from rat neuronal cultures [51], 5hmc-capture from rat brainstem [52], and H4K5ac from rat dorsal striatum [53]. Error margin shows ± sem. FDR was calculated using Benjamini-Hochberg correction after using Wilcox-test

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BMC Genomics

ISSN: 1471-2164

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