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Fig. 3 | BMC Genomics

Fig. 3

From: Evolutionary acquisition of promoter-associated non-coding RNA (pancRNA) repertoires diversifies species-dependent gene activation mechanisms in mammals

Fig. 3

Genomic features of promoter sequences of pancRNA-partnered genes. a. The DNA motifs enriched in the immediately upstream regions of TSSs of pancRNA-partnered genes in the mouse genome (−200 bp to −1 bp relative to the TSS). The E-value of each motif is shown. b. Observed frequency of each DNA motif shown in panel A in the regions around TSSs (−500 bp to +500 bp relative to the TSSs) of each group of genes (total protein-coding genes, genes containing parts of other genes within their promoters, pancRNA-partnered genes, and pancRNA-lacking genes) in the five species’ genomes. c. Sequence conservation (phastCons score) for coding sequence regions (CDS), promoter regions of total genes, those of pancRNA-partnered genes, and those of pancRNA-lacking genes. *** P <0.001; Error bars indicate the first and third quartiles

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BMC Genomics

ISSN: 1471-2164

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