Table 6 Validation of MBD-Seq Differential Expression
CpG | DMR on CHR12 (% methylated) | DMR on CHR19 (% methylated) | ||
|---|---|---|---|---|
High (n = 28) | Low (n = 30) | High (n = 31) | Low (n = 39) | |
1 | 80.8 | 11.1 | 0 | 0 |
2 | 90.0 | 24.0 | 0 | 0 |
3 | 95.5 | 9.1 | 17.2 | 14.7 |
4 | 90.0 | 25.0 | 16.2 | 8.1 |
5 | 81.8 | 25.9 | 6.9 | 3.1 |
6 | 47.8 | 3.5 | 11.1 | 24.3 |
7 | 95.0 | 18.8 | 26.7 | 38.9 |
8 | 80.8 | 13.8 | 38.5 | 38.5 |
9 | 90.0 | 5.3 | 9.7 | 23.9 |
10 | 80.8 | 26.9 | 9.7 | 34.3 |
11 | 90.0 | 35.0 | 10.0 | 37.8 |
12 | 80.8 | 10.5 | 21.4 | 46.2 |
13 | 81.5 | 37.0 | 22.6 | 41.0 |
14 | 90.0 | 70.0 | 26.7 | 43.6 |
15 | Â | Â | 30.0 | 43.6 |
16 | Â | Â | 23.3 | 65.8 |
17 | Â | Â | 34.5 | 55.6 |
18 | Â | Â | 12.9 | 32.4 |
19 | Â | Â | 3.8 | 28.6 |
20 | Â | Â | 22.6 | 8.1 |
21 | Â | Â | 32.3 | 40.0 |
22 | Â | Â | 43.3 | 51.3 |
23 | Â | Â | 37.9 | 44.4 |
Total: | 82.1%* | 20.6% | 20.8% | 34.0%* |