Table 2 Gene Ontology (GO), InterPRO term enriched from C. elegans genes differentially expressed upon Orsay virus or N. parisii infection
From: An evolutionarily conserved transcriptional response to viral infection in Caenorhabditis nematodes
Condition | Go term, InterPRO classification | Human ortholog | Functional annotations | Gene count | FDR |
|---|---|---|---|---|---|
Orsay virus [N2] | IPR026674:ALS2CR12 protein ( C17H1 family) | Yes | N/A | 24 | 6.9E-32 |
| Â | IPR002900:DUF38 | No | F-box associated | 13 | 6.6E-09 |
| Â | IPR007883:DUF713 | No | N/A | 5 | 1.4E-06 |
| Â | IPR002083:MATH | Yes | MATH | 8 | 1.3E-06 |
Orsay virus [rde-1] | IPR026674:ALS2CR12 protein ( C17H1 family) | Yes | N/A | 25 | 2.3E-25 |
| Â | GO:0045087:Innate immune response | N/A | Innate immunity | 23 | 6.2E-13 |
| Â | IPR002083:MATH | Yes | MATH | 14 | 3.1E-09 |
| Â | IPR007883:DUF713 | No | N/A | 7 | 2.9E-08 |
| Â | IPR002900:DUF38 | No | F-box associated | 16 | 3.8E-06 |
| Â | IPR003366:CUB-like domain | No | N/A | 9 | 4.7E-06 |
| Â | IPR000859:CUB domain | Yes | CUB | 8 | 6.1E-04 |
| Â | IPR002867:Zinc finger, C6HC-type | Yes | Ubiquitin related | 4 | 2.1E-02 |
N. parisii [N2] | IPR026674:ALS2CR12 protein ( C17H1 family) | Yes | N/A | 25 | 1.4E-29 |
| Â | IPR007883:DUF713 | No | N/A | 9 | 1.7E-14 |
| Â | IPR002083:MATH | Yes | MATH | 11 | 3.0E-08 |
| Â | IPR002900:DUF38 | No | F-box associated | 13 | 2.5E-06 |
| Â | GO:0045087:Innate immune response | N/A | Innate immunity | 8 | 5.2E-03 |
| Â | IPR001841:Zinc finger, RING-type | Yes | Zinc finger | 8 | 5.9E-03 |
| Â | IPR016186:C-type lectin-like | Yes | C-type lectin-like | 9 | 1.0E-02 |
| Â | GO:0005764:lysosome | N/A | lysosome | 4 | 2.9E-02 |