Table 4 P-values of top 20 genes ranked by the BFGM methods
From: Functional regression method for whole genome eQTL epistasis analysis with sequencing data
| Â | Â | Â | Â | Â | Â | Â | P-value (Interaction) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | Â | SFGM | Â | ||
Gene Expression | Gene 1 | Chr | Marginal (eQTL) | Gene 2 | Chr | Marginal (eQTL) | BFGM | RPKM | DESeq | RNA-min | min P-value |
ULK4 | ULK4 | 3 | 1.45E-01 | C19orf70 | 19 | 7.96E-06 | 0.00E + 00 | 4.17E-01 | 4.98E-01 | 0.00E + 00 | 0.00E + 00 |
ULK4 | ULK4 | 3 | 1.45E-01 | OR10A2 | 11 | 6.04E-15 | 4.07E-305 | 4.33E-05 | 4.97E-03 | 0.00E + 00 | 0.00E + 00 |
CCDC13 | CCDC13 | 3 | 5.60E-01 | TMEM121 | 14 | 9.94E-24 | 2.91E-302 | 4.98E-03 | 1.73E-02 | 1.36E-304 | 2.12E-12 |
ULK4 | ULK4 | 3 | 1.45E-01 | PSMC5 | 17 | 7.30E-23 | 5.72E-267 | 2.79E-05 | 1.50E-03 | 0.00E + 00 | 0.00E + 00 |
ULK4 | ULK4 | 3 | 1.45E-01 | COX5B | 2 | 1.15E-03 | 2.46E-242 | 1.82E-03 | 3.06E-02 | 2.46E-259 | 4.94E-323 |
NKX2-5 | NKX2-5 | 5 | 3.41E-01 | TP53TG3D | 16 | 5.81E-10 | 2.18E-226 | 6.66E-02 | 7.61E-02 | 1.15E-228 | 0.00E + 00 |
ASIC2 | ASIC2 | 17 | 2.24E-02 | RPS16P5 | 6 | 4.08E-05 | 3.39E-226 | 1.12E-01 | 7.77E-02 | 1.76E-158 | 8.01E-237 |
TMEM132E | TMEM132E | 17 | 8.25E-02 | LOC100144602 | 4 | 9.50E-51 | 2.04E-213 | 1.34E-01 | 1.30E-01 | 2.27E-142 | 1.14E-215 |
TMEM98 | TMEM98 | 17 | 6.66E-01 | LOC100144602 | 4 | 9.28E-51 | 4.89E-213 | 8.10E-02 | 1.13E-01 | 4.06E-144 | 6.05E-216 |
SPACA3 | SPACA3 | 17 | 7.13E-02 | LOC100144602 | 4 | 1.41E-50 | 9.18E-211 | 9.72E-03 | 1.21E-02 | 8.78E-141 | 4.90E-214 |
ASIC2 | ASIC2 | 17 | 2.24E-02 | OR5B12 | 11 | 3.09E-05 | 2.89E-205 | 1.97E-01 | 1.18E-01 | 3.63E-141 | 1.18E-259 |
CCL1 | CCL1 | 17 | 6.53E-02 | TINF2 | 14 | 3.57E-22 | 3.85E-205 | 1.23E-01 | 1.31E-01 | 1.52E-157 | 3.33E-210 |
SCN2A | SCN2A | 2 | 1.41E-01 | DEFB4B | 8 | 1.30E-32 | 5.53E-203 | 1.88E-02 | 4.91E-02 | 1.30E-104 | 2.67E-236 |
ZNF254 | ZNF254 | 19 | 4.41E-01 | OR2V1 | 5 | 2.20E-13 | 1.19E-183 | 2.35E-02 | 4.91E-02 | 5.50E-225 | 2.88E-259 |
KRT5 | KRT5 | 12 | 2.45E-02 | OR5K1 | 3 | 1.03E-28 | 3.26E-177 | 1.15E-02 | 2.33E-02 | 2.29E-201 | 5.79E-199 |
FNDC8 | FNDC8 | 17 | 4.83E-01 | LOC100144602 | 4 | 8.13E-49 | 3.46E-172 | 4.38E-03 | 6.19E-02 | 1.20E-124 | 8.03E-175 |
CCT6B | CCT6B | 17 | 3.25E-01 | LOC100144602 | 4 | 8.81E-49 | 4.24E-172 | 7.49E-03 | 3.59E-02 | 3.10E-125 | 1.72E-177 |
TMEM163 | TMEM163 | 2 | 1.16E-01 | HIST1H4H | 6 | 1.79E-09 | 8.50E-170 | 6.74E-02 | 4.79E-02 | 3.40E-112 | 1.19E-25 |
ASIC2 | ASIC2 | 17 | 2.24E-02 | LOC100144602 | 4 | 9.66E-51 | 6.06E-165 | 9.22E-01 | 8.72E-01 | 3.82E-104 | 9.50E-236 |
KRT5 | KRT5 | 12 | 2.45E-02 | IFNA7 | 9 | 3.70E-16 | 2.43E-163 | 2.26E-02 | 1.83E-02 | 2.15E-178 | 2.14E-211 |