Fig. 2
From: High-throughput validation of ceRNA regulatory networks
Target response to perturbations of both predicted ceRNA regulators and non-regulators in MCF7. For each ceRNA target described in Fig. 1b, we plot responses to shRNA-mediated silencing of a predicted ceRNA regulators and b genes not predicted to regulate each ceRNA target in MCF7. Each plot gives the profiling time point after shRNA transfection, and the total number of shRNA targets considered. For silencing of regulators, we provide p values that describe the significance of target responses shown in panel a relative to the response to silencing of other genes shown in panel b. Also provided, adjunct to each scatter plot, are box plots that describe the mean, median, 25 and 75 percentile of the distributions of ranks of the responses of this target relative to all profiled responses to shRNA perturbations