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Table 1 The 16 public RNA-seq data tested

From: Gene dispersion is the key determinant of the read count bias in differential expression analysis of RNA-seq data

Name

Experiment

Test group size

Control group size

Replicate type

Marioni [9]

Human liver vs. kidney

7

7

Technical

MAQC-2 [41]

HBRR vs. SUHRR

7

7

Technical

Oliver [42]

Head tissue of male vs. female Drosophila melanogaster

10

10

Technical

Barutcu [32]

MCF7 vs. MCF10A

3

3

GI

Liu [33]

10nM E2-treated vs. control MCF7

7

7

GI

Li [34]

Androgen-treated vs. control LNCaP cell line

4

3

GI

TCGA KIRC [27]

Human renal clear cell carcinoma vs. matched normal tissue

7

7

Unrelated

TCGA BRCA [43]

Human invasive breast cancer vs. matched normal tissue

7

7

Unrelated

TCGA PRAD [43]

Human prostate adenocarcinoma vs. matched normal tissue

15

15

Unrelated

Tuch [44]

Human oral squamous cell carcinoma vs. matched normal tissue

3

3

Unrelated

ModencodeFly [37]

L1 Larvae vs. Embryos (12–14 h)

4

5

Technical

White pre-pupae (12 h) vs. L1 Larvae

5

4

Technical

Adult male (1 day) vs. White pre-pupae (12 h)

5

5

Technical

Pooled Larvae vs. pooled embryos (12–24 h)

6

6

Unrelated

Pooled pupae vs. pooled larvae

6

6

Unrelated

Pooled adult male vs. pooled pupae

3

6

Unrelated

  1. Abbreviation: GI genetically identical, HBRR Ambion First Choice Human Brain Reference RNA, SUHRR Stratagene Universal Human Reference RNA