Fig. 7
From: Genome-scale analysis of regulatory protein acetylation enzymes from photosynthetic eukaryotes
Alignment of Select HDT-family KDACs from photosynthetic eukaryotes. Representative dicots (A. thaliana & P. trichocarpa), monocots (O. sativa), moss (P. patens), bryophytes (S. moellendorfii) and chromoalveolates (E. huxleyi and G. theta) are shown. The short half-life motif is conserved in the extreme n-terminus of all HDT KDACs (yellow) along with the first 100 amino acids of each HDT KDAC. Stretches of unique protein regions can be observed in M. brevicolis, G. theta and P. patens HDT KDACs (blue dashes). As well, absence of conserved land plant protein regions is also observed (shaded blue). Arrows (red) denote amino acids involved in HDT deacetylase activity. Underlined (solid red) are the larger proposed catalytic motifs. A highly conserved acidic amino acid stretch is also depicted (Underlined; solid black). M. brevecolis maintains a large n-terminal region not conserved amongst other HDT KDACs (not shown). This may be an unannotated splice variant or a mis-annotation in the M. brevicolis genome. The n-terminal methionine depicted here was highly conserved across all HDT-family KDACs found in this study