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Table 1 Sensitivity and PPV for RepProfile and competing methods in the three different simulations

From: Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible

Exact Rep

Sens.

PPV

 RepProfile

0.94

0.99

 Porath

0.07

1.0

 EER uniq

0.36

0.99

 EER +rep

0.90

0.14

Clone

 RepProfile

0.95

1.0

 Porath

0.13

0.97

 EER uniq

0.55

0.82

 EER +rep

0.91

0.42

Random

 RepProfile

0.87

0.99

 Porath

0.50

0.98

 EER uniq

0.70

0.98

 EER +rep

0.86

0.74

  1. Top: Simulation from 24 identical copies of a hypothetical repeat. Middle: Simulation of editing predicted by clones. Bottom: Random hyper-editing of FB4_DM