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Table 6 Predicted cathelicidin antimicrobial peptide gene sequences

From: The Komodo dragon (Varanus komodoensis) genome and identification of innate immunity genes and clusters

Cathelicidin Gene

Predicted Sequence of Precursor Protein

Cathelicidin2_VARKO

MELFLLGVTLLMLGVPGATSPPLDAPSALLPRDVARMAVEDFNQEAEGQAVFRLLKLKHTHKVKFRWGFHFSLNFTIKETHCRKSDNYRIENCRYKTKGPIQDCSAQVSVLNFMPDSPLTSVKCRRGNGRGSRKAQPSAMLQAEERQPQVHVEVYLPSAYSIAALSVAEEEPSRPAARPH

Cathelicidin4.1_VARKO

MASPWALPLMLLLLGMVGAAPSTAPPSSYDQVIAAAVDIYNQQQKPEYAFRLLEAEPQPDWNSSAQTNQVLRFSIKETVCRPSEKADLSQCDYKPDGVDRDCSGFYSPQQSPPTIMVQCEDVDQELDRVTRFRWRRFFRKAKRFLKRHGVSIAIGTVRLLRRFG

Cathelicidin4.2_VARKO

MASPRALLLMLLLLRTVGAAPSAAPPSSYEQVIAAAVDTYNQQQKPAYAFRLLEAEPQPDWNPSAGTTQPLRFSIKETVCRPSEKADLSQCDYKPNGVDRDCSGFYSPQQQSPPTILVQCEDLDRVTRRRWRRFFQKAKRFVKRHGVSIAVGAYRIIG

  1. Full predicted animo acid sequence of Komodo cathelicidin proteins. Note, the Cathelicidin2_VARKO lacks the VTR sequence that is typically present in other reptile cathleicidin precursor proteins, including Cathelicidin4.1_VARKO and Cathelicidin4.2_VARKO
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BMC Genomics

ISSN: 1471-2164

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