Fig. 2

Identification of predominant regulatory alternative splicing (RAS) events between OA and healthy samples. (A) Bar plot showing the number of different RAS types identified by SUVA in OA samples. (B) Bar plot showing RAS with different pSAR (proportion of each SUVA AS event reads). RAS with pSAR ≥ 50% were labeled. (C) Principal component analysis (PCA) based on RAS with pSAR ≥ 50%. The ellipse for each group is the confidence ellipse. (D) The heatmap showing the splicing ratio of RAS of all samples (pSAR ≥ 50%). (E) Bar plot exhibiting the most enriched GO pathways of the RAS with pSAR ≥ 50%.