| Range, mmol/L; mg/dL | No. of events (%) | Unadjusted | Adjusted model 1a | Adjusted model 2b | ||||
---|---|---|---|---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | ||||
Potassium | < 5th | 2.50–3.59 | 146 (19.84) | 1.38 (1.15,1.66) | 0.001 | 1.56 (1.29,1.89) | < 0.001 | 1.37 (1.13,1.66) | 0.001 |
5 to < 20th | 3.60–4.09 | 386 (17.48) | 1.05 (0.92,1.21) | 0.45 | 1.12 (0.98,1.29) | 0.11 | 1.08 (0.94,1.24) | 0.25 | |
20 to < 40th | 4.10–4.29 | 493 (16.75) | 1.01 (0.89,1.14) | 0.93 | 1.03 (0.91,1.17) | 0.61 | 1.04 (0.91,1.18) | 0.57 | |
40 to < 60th | 4.30–4.49 | 489 (16.60) | 1.00 (Reference) | – | 1.00 (Reference) | – | 1.00 (Reference) | – | |
60 to < 80th | 4.50–4.79 | 506 (17.19) | 1.07 (0.94,1.21) | 0.32 | 1.01 (0.89,1.14) | 0.91 | 1.01 (0.89,1.15) | 0.85 | |
80 to < 95th | 4.80–5.19 | 394 (17.84) | 1.09 (0.96,1.25) | 0.19 | 1.04 (0.90,1.19) | 0.61 | 1.06 (0.93,1.21) | 0.40 | |
≥ 95th | 5.20–6.50 | 125 (16.98) | 1.08 (0.89,1.32) | 0.44 | 1.00 (0.82,1.21) | 0.96 | 1.02 (0.84,1.25) | 0.83 | |
P for trend |  |  | 0.002 |  | < 0.001 |  | < 0.001 |  | |
Magnesium | < 5th | 0.50–1.39 | 166 (22.55) | 1.76 (1.48,2.11) | < 0.001 | 1.85 (1.54,2.21) | < 0.001 | 1.43 (1.19,1.72) | < 0.001 |
5 to < 20th | 1.40–1.49 | 420 (19.02) | 1.25 (1.09,1.43) | 0.17 | 1.36 (1.19,1.55) | < 0.001 | 1.22 (1.06,1.39) | 0.004 | |
20 to < 40th | 1.50–1.59 | 492 (16.71) | 1.01 (0.89,1.14) | 0.93 | 1.01 (0.89,1.14) | 0.90 | 0.98 (0.87,1.12) | 0.80 | |
40 to < 60th | 1.60–1.69 | 500 (16.98) | 1.00 (Reference) | – | 1.00 (Reference) | – | 1.00 (Reference) | – | |
60 to < 80th | 1.70–1.79 | 495 (16.81) | 1.00 (0.88,1.13) | 0.96 | 0.94 (0.83,1.06) | 0.31 | 0.97 (0.85,1.10) | 0.59 | |
80 to < 95th | 1.80–1.89 | 338 (15.31) | 0.88 (0.77,1.02) | 0.09 | 0.84 (0.73,0.96) | 0.01 | 0.89 (0.78,1.03) | 0.11 | |
≥ 95th | 1.90–3.10 | 128 (17.39) | 1.01 (0.83,1.23) | 0.90 | 0.95 (0.78,1.16) | 0.64 | 0.97 (0.80,1.19) | 0.78 | |
P for trend |  |  | < 0.001 |  | < 0.001 |  | < 0.001 |  | |
Phosphate | < 5th | 1.00-2.59 | 153 (20.79) | 1.26 (1.05,1.52) | 0.01 | 1.07 (0.89,1.29) | 0.48 | 1.00 (0.83,1.21) | 0.97 |
5 to < 20th | 2.60–2.99 | 397 (17.98) | 1.10 (0.96,1.26) | 0.16 | 1.01 (0.88,1.16) | 0.92 | 0.98 (0.85,1.12) | 0.73 | |
20 to < 40th | 3.00-3.29 | 491 (16.68) | 1.02 (0.90,1.16) | 0.79 | 0.99 (0.87,1.13) | 0.89 | 0.99 (0.87,1.12) | 0.83 | |
40 to < 60th | 3.30–3.49 | 478 (16.23) | 1.00 (Reference) | – | 1.00 (Reference) | – | 1.00 (Reference) | – | |
60 to < 80th | 3.50–3.79 | 513 (17.43) | 1.07 (0.94,1.21) | 0.32 | 1.13 (0.99,1.28) | 0.06 | 1.12 (0.99,1.27) | 0.08 | |
80 to < 95th | 3.80–4.19 | 383 (17.35) | 1.09 (0.95,1.25) | 0.23 | 1.20 (1.05,1.38) | 0.01 | 1.18 (1.03,1.36) | 0.02 | |
≥ 95th | 4.20–9.10 | 124 (16.85) | 1.14 (0.93,1.39) | 0.20 | 1.33 (1.09,1.63) | 0.01 | 1.32 (1.07,1.62) | 0.01 | |
P for trend |  |  | < 0.001 |  | < 0.001 |  | < 0.001 |  | |
Calcium | < 5th | 7.28–9.23 | 122 (16.58) | 0.86 (0.71,1.06) | 0.15 | 0.87 (0.71,1.07) | 0.18 | 0.90 (0.74,1.11) | 0.33 |
5 to < 20th | 9.24–9.53 | 364 (16.49) | 0.89 (0.77,1.02) | 0.08 | 0.90 (0.79,1.03) | 0.13 | 0.91 (0.79,1.04) | 0.16 | |
20 to < 40th | 9.54–9.77 | 497 (16.88) | 0.94 (0.83,1.06) | 0.33 | 0.97 (0.86,1.10) | 0.68 | 0.97 (0.86,1.10) | 0.67 | |
40 to < 60th | 9.78–9.97 | 512 (17.39) | 1.00 (Reference) | – | 1.00 (Reference) | – | 1.00 (Reference) | – | |
60 to < 80th | 9.98–10.21 | 540 (18.34) | 1.09 (0.96,1.23) | 0.19 | 1.10 (0.97,1.24) | 0.13 | 1.07 (0.95,1.22) | 0.25 | |
80 to < 95th | 10.22–10.57 | 376 (17.03) | 1.05 (0.91,1.20) | 0.51 | 1.10 (0.96,1.26) | 0.18 | 1.03 (0.90,1.18) | 0.65 | |
≥ 95th | 10.58–13.56 | 128 (17.39) | 1.17 (0.96,1.43) | 0.12 | 1.20 (0.98,1.47) | 0.07 | 1.08 (0.88,1.32) | 0.45 | |
P for trend | Â | Â | 0.02 | Â | 0.02 | Â | 0.50 | Â |