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Fig. 6 | BMC Genomics

Fig. 6

From: A transcriptome-wide identification of ATP-binding cassette (ABC) transporters revealed participation of ABCB subfamily in abiotic stress management of Glycyrrhiza glabra L

Fig. 6

Schematic representation of IAA transportation under the influence of NPA. IAA transportation is mediated by ABCBs. A positive regulator, TWD1, PGP1-mediated auxin transporter, acts as a chaperone in association with ABCB subfamily for transportation from Endoplasmic reticulum to Plasma membrane. N-1-naphthylphthalamic acid (NPA), a polar auxin transport inhibitor, binds with high affinity to ABCBs and TWD1 complex of plant membranes [76, 77]. NPA (10 µM) disrupts TWD1-ABCB interaction resulting in inhibition of auxin transportation. Blue arrows indicate auxin biosynthesis pathways. Brown dotted arrows indicates trafficking of ABCB transporter by TWD1 from Endoplasmic reticulum to Plasma membrane, when no NPA is present. In the presence of NPA (10 µM), its binds to the ABCB –TWDI Complex and blocks the transportation

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