Fig. 1From: Identification of skewed X chromosome inactivation using exome and transcriptome sequencing in patients with suspected rare genetic diseaseDensity plot for 135 GTEx reference females displaying the percentage of statistically skewed variant positions when tested on a per sample basis. The red dotted line indicates the selected threshold for defining individuals with X-skew versus patients without X-skew. The threshold was selected to fall within the range of the reported frequency of X-skew in the general population and aligned to a local minimum in the density plotBack to article page