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Fig. 8 | BMC Genomics

Fig. 8

From: Metabolomics and proteomics insights into subacute ruminal acidosis etiology and inhibition of proliferation of yak rumen epithelial cells in vitro

Fig. 8

Overview of the main proteomic and metabolomic changes induced by SCFA, Aci, and LPS factors related to ruminal acidosis respectively. (a) Integrated metabolic network pathways of metabolic disorders caused by factors related to SARA in YRECs. Different arrow colors represent different factors associated with SARA, with upward arrows representing upregulated expression and downward arrows representing down-regulated expression. The metabolites highlighted in red within the enriched metabolic signaling pathways affected by different treatment groups in YRECs are all significantly different (P < 0.05). (b) Interaction network of differentially expressed proteins in major changed pathways exposed by SCFA, Aci, and LPS. The green ovals on the periphery of the network represent proteins with significantly differential expression in the enriched signaling pathways (P < 0.05). (c) Proposed signaling and metabolic pathways for SCFA, Aci, and LPS-induced epithelial toxic injury in YRECs

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BMC Genomics

ISSN: 1471-2164

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