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Table 5 The prominent process in GO enrichment analysis

From: Transcriptome exploration of ferroptosis-related genes in TGFβ- induced lens epithelial to mesenchymal transition during posterior capsular opacification development

Category

GOID

Description

GeneRatio

P value

geneName

Common genes

BP

GO:0006979

Response to oxidative stress

11/38

1.53E-09

NOX4/SLC7A11/KLF2/CYGB

/PTGS2/NQO1/MGST1/AKR1C3

/TXNRD1/TXNIP/MAP3K5

NOX4/SLC7A11/KLF2

/CYGB/PTGS2/NQO1

/MGST1/AKR1C3/TXNRD1

/TXNIP/MAP3K5/PDK4

/IL1B/CAV1/DPP4

/LGMN/AQP5/ALDH3A2

/AKR1C1

BP

GO:0072593

Reactive oxygen species metabolic process

8/38

6.63E-08

NOX4/IL1B/KLF2/PTGS2

/NQO1/CAV1/

AKR1C3/PDK4

BP

GO:0006809

Nitric oxide biosynthetic process

5/38

3.66E-07

IL1B/KLF2/PTGS

2/NQO1/CAV1

CC

GO:0045177

Apical part of cell

5/37

0.000818234

DPP4/LGMN/NOX4

/AQP5/MGST1

CC

GO:0005778

Peroxisomal membrane

2/37

0.006112096

MGST1/ALDH3A2

CC

GO:0031903

Microbody membrane

2/37

0.006112096

MGST1/ALDH3A2

MF

GO:0016209

Antioxidant activity

5/38

1.07E-06

CYGB/PTGS2/NQO1

/MGST1/TXNRD1

MF

GO:0016651

Oxidoreductase activity, acting on NAD(P)H

5/38

4.66E-06

NOX4/NQO1/AKR1C3

/AKR1C1/TXNRD1

MF

GO:0004601

Peroxidase activity

3/38

0.000122681

CYGB/PTGS2/MGST1