Table 2 Analysis of variations in N-glycosylation and phosphorylation sites in the 87 sequences of Omicron BA.2.76 in Jining City, compared with Wuhan-Hu-1
From: Comprehensive genomic analysis of the SARS-CoV-2 Omicron variant BA.2.76 in Jining City, China, 2022
Protein | Amino acid positions of Wuhan-Hu-1 | Amino acid positions in the Jining City sequence | Number of mutations in the 87 sequences of Jining City | Changes in N-glycosylation sites or phosphorylation sites |
|---|---|---|---|---|
Plpro | NIT22-24 | NII22-24 | 87 | Loss of N22 glycosylation site |
S | NLT17-19 | NLI17-19 | 87 | Loss of N17 glycosylation site |
S | YLT248-250 | NLT248-250 | 87 | Addition of N248 glycosylation site |
NSP1 | S135 | R135 | 87 | Loss of S135 phosphorylation site |
Plpro | T24 | I24 | 87 | Loss of T24 phosphorylation site |
Plpro | G489 | S489 | 87 | Addition of S489 phosphorylation site |
NSP6 | S106 | - | 87 | Loss of S263 phosphorylation site |
helicase | S263 | F263 | 87 | Loss of T24 phosphorylation site |
S | T19 | I19 | 87 | Loss of T19 phosphorylation site |
S | S375 | F375 | 87 | Loss of S375 phosphorylation site |
S | T376 | A376 | 87 | Loss of T376 phosphorylation site |
S | S477 | N477 | 87 | Loss of S477 phosphorylation site |
S | T478 | K478 | 87 | Loss of T478 phosphorylation site |
S | T547 | I547 | 1 | Loss of T547 phosphorylation site |
S | L24 | S24 | 87 | Addition of S24 phosphorylation site |
S | R408 | S408 | 87 | Addition of S408 phosphorylation site |
S | H655 | Y655 | 87 | Addition of Y655 phosphorylation site |
ORF3a | T223 | I223 | 87 | Loss of T223 phosphorylation site |
E | S55 | F55 | 1 | Loss of S55 phosphorylation site |
N | S33 | - | 87 | Loss of S33 phosphorylation site |
N | S413 | T413 | 87 | Loss of S413 phosphorylation site |