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Table 4 Descriptive statistics for discovery and replication datasets

From: Germline genetic regulation of the colorectal tumor immune microenvironment

T Cell Repertoire Characteristics

Discovery

Replication

 

MECC

CLX

CRCGEN

NHS & HPFS

Abundance

2395

 

92

 

162

 

-

 

Clonality

2395

 

94

 

162

 

-

 

TILs

2876

 

97

 

-

 

505

 

Cutoff

0 vs. Any

 

< 1 vs. >=1

   

0 vs. Any

 
 

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Age

69.5

12.2

70.9

9.03

67.60

10.04

69.3

8.84

 

Count

%

Count

%

Count

%

Count

%

Sex

        

Female

1383

48.1

28

28.9

61

62.4

250

49.5

Male

1493

51.9

69

71.1

101

37.7

255

50.5

Race

        

White

2876

100.0

97

100.0

162

100.0

257

50.9

Other/Unknown

--

--

--

--

--

--

6

1.2

Missing

--

--

--

--

--

--

242

47.9

Stage

        

I

467

16.2

0

0.0

0

0.0

139

27.5

II

1319

45.8

97

100.0

162

100.0

164

32.5

III

540

18.8

0

0.0

0

0.0

122

24.2

IV

302

10.5

0

0.0

0

0.0

42

8.3

Missing

250

8.7

0

0.0

0

0.0

38

7.5

MSI Status

        

Stable

2249

78.2

97

100.0

162

100.0

372

73.6

Instable

417

14.5

0

0.0

0

0.0

67

13.3

Missing

210

7.3

--

--

--

--

66

13.1