Volume 11 Supplement 5

Proceedings of the 5th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-meeting 2009)

Proceedings

http://www.ab3c.org

5th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-meeting 2009). Go to conference site.

Angra Dos Reis, RJ, Brazil

18-22 October 2009

  1. Proceedings

    Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis

    The link between reproductive life history and incidence of ovarian tumors is well known. Periods of reduced ovulations may confer protection against ovarian cancer. Using phenotypic data available for mouse, ...

    Ulises Urzúa, Garrison A Owens, Gen-Mu Zhang, James M Cherry, John J Sharp and David J Munroe

    BMC Genomics 2010 11(Suppl 5):S1

    Published on: 22 December 2010

  2. Proceedings

    RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion

    The thymus is a central lymphoid organ, in which bone marrow-derived T cell precursors undergo a complex process of maturation. Developing thymocytes interact with thymic microenvironment in a defined spatial ...

    Leandra Linhares-Lacerda, Marcelo Ribeiro-Alves, Ana Cristina Martins de Almeida Nogueira, Daniella Areas Mendes-da-Cruz, Danielle Aparecida Magalhães, Mireille Dardenne, Geraldo Aleixo Passos and Wilson Savino

    BMC Genomics 2010 11(Suppl 5):S2

    Published on: 22 December 2010

  3. Proceedings

    Disclosing ambiguous gene aliases by automatic literature profiling

    Retrieving pertinent information from biological scientific literature requires cutting-edge text mining methods which may be able to recognize the meaning of the very ambiguous names of biological entities. A...

    Roney S Coimbra, Dana E Vanderwall and Guilherme C Oliveira

    BMC Genomics 2010 11(Suppl 5):S3

    Published on: 22 December 2010

  4. Proceedings

    Alternative splicing enriched cDNA libraries identify breast cancer-associated transcripts

    Alternative splicing (AS) is a central mechanism in the generation of genomic complexity and is a major contributor to transcriptome and proteome diversity. Alterations of the splicing process can lead to dere...

    Elisa N Ferreira, Maria CR Rangel, Pedro F Galante, Jorge E de Souza, Gustavo C Molina, Sandro J de Souza and Dirce M Carraro

    BMC Genomics 2010 11(Suppl 5):S4

    Published on: 22 December 2010

  5. Proceedings

    How does heparin prevent the pH inactivation of cathepsin B? Allosteric mechanism elucidated by docking and molecular dynamics

    Cathepsin B (catB) is a promising target for anti-cancer drug design due to its implication in several steps of tumorigenesis. catB activity and inhibition are pH-dependent, making it difficult to identify eff...

    Mauricio GS Costa, Paulo R Batista, Cláudio S Shida, Charles H Robert, Paulo M Bisch and Pedro G Pascutti

    BMC Genomics 2010 11(Suppl 5):S5

    Published on: 22 December 2010

  6. Proceedings

    Unraveling the molecular mechanisms of nitrogenase conformational protection against oxygen in diazotrophic bacteria

    G. diazotrophicus and A. vinelandii are aerobic nitrogen-fixing bacteria. Although oxygen is essential for the survival of these organisms, it irreversibly inhibits nitrogenase, the complex responsible for nitrog...

    Letícia MS Lery, Mainá Bitar, Mauricio GS Costa, Shaila CS Rössle and Paulo M Bisch

    BMC Genomics 2010 11(Suppl 5):S7

    Published on: 22 December 2010

  7. Proceedings

    SIGLa: an adaptable LIMS for multiple laboratories

    The need to manage large amounts of data is a clear demand for laboratories nowadays. The use of Laboratory Information Management Systems (LIMS) to achieve this is growing each day. A LIMS is a complex comput...

    Alexandre Melo, Alessandra Faria-Campos, Daiane Mariele DeLaat, Rodrigo Keller, Vinícius Abreu and Sérgio Campos

    BMC Genomics 2010 11(Suppl 5):S8

    Published on: 22 December 2010

  8. Proceedings

    Decreasing the number of false positives in sequence classification

    A large number of probabilistic models used in sequence analysis assign non-zero probability values to most input sequences. To decide when a given probability is sufficient the most common way is bayesian bin...

    Ariane Machado-Lima, André Yoshiaki Kashiwabara and Alan Mitchell Durham

    BMC Genomics 2010 11(Suppl 5):S10

    Published on: 22 December 2010

  9. Proceedings

    The role of exon shuffling in shaping protein-protein interaction networks

    Physical protein-protein interaction (PPI) is a critical phenomenon for the function of most proteins in living organisms and a significant fraction of PPIs are the result of domain-domain interactions. Exon s...

    Douglas V Cancherini, Gustavo S França and Sandro J de Souza

    BMC Genomics 2010 11(Suppl 5):S11

    Published on: 22 December 2010

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