Volume 13 Supplement 4

SNP-SIG 2011: Identification and annotation of SNPs in the context of structure, function and disease

Proceedings

Edited by Yana Bromberg and Emidio Capriotti

SNP-SIG 2011: Identification and annotation of SNPs in the context of structure, function and disease. Go to conference site.

Vienna, Austria

15 July 2011

  1. Proceedings

    Prioritization of pathogenic mutations in the protein kinase superfamily

    Most of the many mutations described in human protein kinases are tolerated without significant disruption of the corresponding structures or molecular functions, while some of them have been associated to a v...

    Jose MG Izarzugaza, Angela del Pozo, Miguel Vazquez and Alfonso Valencia

    BMC Genomics 2012 13(Suppl 4):S3

    Published on: 18 June 2012

  2. Proceedings

    Predict impact of single amino acid change upon protein structure

    Amino acid point mutations (nsSNPs) may change protein structure and function. However, no method directly predicts the impact of mutations on structure. Here, we compare pairs of pentamers (five consecutive r...

    Christian Schaefer and Burkhard Rost

    BMC Genomics 2012 13(Suppl 4):S4

    Published on: 18 June 2012

  3. Proceedings

    On the effect of protein conformation diversity in discriminating among neutral and disease related single amino acid substitutions

    Non-synonymous coding SNPs (nsSNPs) that are associated to disease can also be related with alterations in protein stability. Computational methods are available to predict the effect of single amino acid subs...

    Ezequiel Juritz, Maria Silvina Fornasari, Pier Luigi Martelli, Piero Fariselli, Rita Casadio and Gustavo Parisi

    BMC Genomics 2012 13(Suppl 4):S5

    Published on: 18 June 2012

  4. Proceedings

    Predicting cancer-associated germline variations in proteins

    Various computational methods are presently available to classify whether a protein variation is disease-associated or not. However data derived from recent technological advancements make it feasible to exten...

    Pier Luigi Martelli, Piero Fariselli, Eva Balzani and Rita Casadio

    BMC Genomics 2012 13(Suppl 4):S8

    Published on: 18 June 2012

  5. Proceedings

    Domain landscapes of somatic mutations in cancer

    Large-scale tumor sequencing projects are now underway to identify genetic mutations that drive tumor initiation and development. Most studies take a gene-based approach to identifying driver mutations, highli...

    Nathan L Nehrt, Thomas A Peterson, DoHwan Park and Maricel G Kann

    BMC Genomics 2012 13(Suppl 4):S9

    Published on: 18 June 2012

  6. Proceedings

    Disease-related mutations predicted to impact protein function

    Non-synonymous single nucleotide polymorphisms (nsSNPs) alter the protein sequence and can cause disease. The impact has been described by reliable experiments for relatively few mutations. Here, we study pred...

    Christian Schaefer, Yana Bromberg, Dominik Achten and Burkhard Rost

    BMC Genomics 2012 13(Suppl 4):S11

    Published on: 18 June 2012

Portable peer review

The editors of BMC Genomics support initiatives that expedite the peer review process and are happy to consider manuscripts that have been reviewed in Axios Review or Peerage of Science. Please indicate in your cover letter if this applies to your manuscript.

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