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Volume 9 Supplement 1

The 2007 International Conference on Bioinformatics & Computational Biology (BIOCOMP'07)

Research

Edited by Jack Y Jang, Mary Qu Yang, Mengxia (Michelle) Zhu, Youping Deng and Hamid R Arabnia

The 2007 International Conference on Bioinformatics & Computational Biology (BIOCOMP'07). Go to conference site.

Las Vegas, NV, USA25-28 June 2007

  1. Proteins are involved in many interactions with other proteins leading to networks that regulate and control a wide variety of physiological processes. Some of these proteins, called hub proteins or hubs, bind...

    Authors: Christopher J Oldfield, Jingwei Meng, Jack Y Yang, Mary Qu Yang, Vladimir N Uversky and A Keith Dunker
    Citation: BMC Genomics 2008 9(Suppl 1):S1
  2. Since the high dimensionality of gene expression microarray data sets degrades the generalization performance of classifiers, feature selection, which selects relevant features and discards irrelevant and redu...

    Authors: Jack Y Yang, Guo-Zheng Li, Hao-Hua Meng, Mary Qu Yang and Youping Deng
    Citation: BMC Genomics 2008 9(Suppl 1):S3
  3. Biclustering of gene expression data searches for local patterns of gene expression. A bicluster (or a two-way cluster) is defined as a set of genes whose expression profiles are mutually similar within a subs...

    Authors: Jiajun Gu and Jun S Liu
    Citation: BMC Genomics 2008 9(Suppl 1):S4
  4. Comprehensive evaluation of common genetic variations through association of single nucleotide polymorphisms (SNPs) with complex human diseases on the genome-wide scale is an active area in human genome resear...

    Authors: Qingzhong Liu, Jack Yang, Zhongxue Chen, Mary Qu Yang, Andrew H Sung and Xudong Huang
    Citation: BMC Genomics 2008 9(Suppl 1):S6
  5. An important subfamily of membrane proteins are the transmembrane α-helical proteins, in which the membrane-spanning regions are made up of α-helices. Given the obvious biological and medical significance of t...

    Authors: Jack Y Yang, Mary Qu Yang, A Keith Dunker, Youping Deng and Xudong Huang
    Citation: BMC Genomics 2008 9(Suppl 1):S7
  6. Iron homeostasis is a key metabolism for most organisms. In many bacterial species, coordinate regulation of iron homeostasis depends on the protein product of a Fur gene. Fur also plays roles in virulence, ac...

    Authors: Yunfeng Yang, Daniel P Harris, Feng Luo, Liyou Wu, Andrea B Parsons, Anthony V Palumbo and Jizhong Zhou
    Citation: BMC Genomics 2008 9(Suppl 1):S11
  7. The most common application of microarray technology in disease research is to identify genes differentially expressed in disease versus normal tissues. However, it is known that, in complex diseases, phenotyp...

    Authors: Min Xu, Ming-Chih J Kao, Juan Nunez-Iglesias, Joseph R Nevins, Mike West and Xianghong Jasmine Zhou
    Citation: BMC Genomics 2008 9(Suppl 1):S12
  8. The budding yeast Saccharomyces cerevisiae is a eukaryotic organism with extensive genetic redundancy. Large-scale gene deletion analysis has shown that over 80% of the ~6200 predicted genes are nonessential and ...

    Authors: Jinghe Mao, Tanwir Habib, Ming Shenwu, Baobin Kang, Wilbur Allen, LaShonda Robertson, Jack Y Yang and Youping Deng
    Citation: BMC Genomics 2008 9(Suppl 1):S14
  9. Explosive compounds such as TNT and RDX are recalcitrant contaminants often found co-existing in the environment. In order to understand the joint effects of TNT and RDX on earthworms, an important ecological ...

    Authors: Ping Gong, Xin Guan, Laura S Inouye, Youping Deng, Mehdi Pirooznia and Edward J Perkins
    Citation: BMC Genomics 2008 9(Suppl 1):S15
  10. Occurrence of protein in the cell is an important step in understanding its function. It is highly desirable to predict a protein's subcellular locations automatically from its sequence. Most studied methods f...

    Authors: Tanwir Habib, Chaoyang Zhang, Jack Y Yang, Mary Qu Yang and Youping Deng
    Citation: BMC Genomics 2008 9(Suppl 1):S16
  11. Massively parallel pyrosequencing is a high-throughput technology that can sequence hundreds of thousands of DNA/RNA fragments in a single experiment. Combining it with immunoprecipitation-based biochemical as...

    Authors: Xin Wang, Guohua Wang, Changyu Shen, Lang Li, Xinguo Wang, Sean D Mooney, Howard J Edenberg, Jeremy R Sanford and Yunlong Liu
    Citation: BMC Genomics 2008 9(Suppl 1):S17
  12. Transcription factors (TFs) have multiple combinatorial forms to regulate the transcription of a target gene. For example, one TF can help another TF to stabilize onto regulatory DNA sequence and the other TF ...

    Authors: Chieh-Chun Chen, Xin-Guang Zhu and Sheng Zhong
    Citation: BMC Genomics 2008 9(Suppl 1):S18
  13. This is a first report, using our MotifModeler informatics program, to simultaneously identify transcription factor (TF) and microRNA (miRNA) binding sites from gene expression microarray data. Based on the assum...

    Authors: Guohua Wang, Xin Wang, Yadong Wang, Jack Y Yang, Lang Li, Kenneth P Nephew, Howard J Edenberg, Feng C Zhou and Yunlong Liu
    Citation: BMC Genomics 2008 9(Suppl 1):S19
  14. The ability to rapidly map millions of oligonucleotide fragments to a reference genome is crucial to many high throughput genomic technologies.

    Authors: Wei Li, Jason S Carroll, Myles Brown and X Shirley Liu
    Citation: BMC Genomics 2008 9(Suppl 1):S20
  15. The prognosis for many cancers could be improved dramatically if they could be detected while still at the microscopic disease stage. It follows from a comprehensive statistical analysis that a number of antig...

    Authors: Jack Y Yang, Mary Qu Yang, Zuojie Luo, Yan Ma, Jianling Li, Youping Deng and Xudong Huang
    Citation: BMC Genomics 2008 9(Suppl 1):S23
  16. Genome evolution is shaped not only by nucleotide substitutions, but also by structural changes including gene and genome duplications, insertions, deletions and gene order rearrangements. The most popular met...

    Authors: Feng Yue, Liying Cui, Claude W dePamphilis, Bernard ME Moret and Jijun Tang
    Citation: BMC Genomics 2008 9(Suppl 1):S25

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