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  1. Research article

    Comparative genomics of Eucalyptus and Corymbia reveals low rates of genome structural rearrangement

    Previous studies suggest genome structure is largely conserved between Eucalyptus species. However, it is unknown if this conservation extends to more divergent eucalypt taxa. We performed comparative genomics be...

    J. B. Butler, R. E. Vaillancourt, B. M. Potts, D. J. Lee, G. J. King, A. Baten, M. Shepherd and J. S. Freeman

    BMC Genomics 2017 18:397

    Published on: 22 May 2017

  2. Research article

    Transversions have larger regulatory effects than transitions

    Transversions (Tv’s) are more likely to alter the amino acid sequence of proteins than transitions (Ts’s), and local deviations in the Ts:Tv ratio are indicative of evolutionary selection on genes. Whether the...

    Cong Guo, Ian C. McDowell, Michael Nodzenski, Denise M. Scholtens, Andrew S. Allen, William L. Lowe and Timothy E. Reddy

    BMC Genomics 2017 18:394

    Published on: 19 May 2017

  3. Research article

    Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle

    Single nucleotide polymorphism (SNP) arrays for domestic cattle have catalyzed the identification of genetic markers associated with complex traits for inclusion in modern breeding and selection programs. Usin...

    Christopher M. Seabury, David L. Oldeschulte, Mahdi Saatchi, Jonathan E. Beever, Jared E. Decker, Yvette A. Halley, Eric K. Bhattarai, Maral Molaei, Harvey C. Freetly, Stephanie L. Hansen, Helen Yampara-Iquise, Kristen A. Johnson, Monty S. Kerley, JaeWoo Kim, Daniel D. Loy, Elisa Marques…

    BMC Genomics 2017 18:386

    Published on: 18 May 2017

  4. Research article

    Higher-order organisation of extremely amplified, potentially functional and massively methylated 5S rDNA in European pikes (Esox sp.)

    Pikes represent an important genus (Esox) harbouring a pre-duplication karyotype (2n = 2x = 50) of economically important salmonid pseudopolyploids. Here, we have characterized the 5S ribosomal RNA genes (rDNA) i...

    Radka Symonová, Konrad Ocalewicz, Lech Kirtiklis, Giovanni Battista Delmastro, Šárka Pelikánová, Sonia Garcia and Aleš Kovařík

    BMC Genomics 2017 18:391

    Published on: 18 May 2017

  5. Research article

    The midgut transcriptome of Aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape

    The mosquito Aedes aegypti is the primary vector for medically important arthropod-borne viruses, including chikungunya virus (CHIKV). Following oral acquisition, an arbovirus has to persistently infect several o...

    Shengzhang Dong, Susanta K. Behura and Alexander W. E. Franz

    BMC Genomics 2017 18:382

    Published on: 15 May 2017

  6. Methodology article

    Transcription factor-associated combinatorial epigenetic pattern reveals higher transcriptional activity of TCF7L2-regulated intragenic enhancers

    Recent studies have suggested that combinations of multiple epigenetic modifications are essential for controlling gene expression. Despite numerous computational approaches have been developed to decipher the...

    Qi Liu, Russell Bonneville, Tianbao Li and Victor X. Jin

    BMC Genomics 2017 18:375

    Published on: 12 May 2017

  7. Research article

    Cattle genome-wide analysis reveals genetic signatures in trypanotolerant N’Dama

    Indigenous cattle in Africa have adapted to various local environments to acquire superior phenotypes that enhance their survival under harsh conditions. While many studies investigated the adaptation of overa...

    Soo-Jin Kim, Sojeong Ka, Jung-Woo Ha, Jaemin Kim, DongAhn Yoo, Kwondo Kim, Hak-Kyo Lee, Dajeong Lim, Seoae Cho, Olivier Hanotte, Okeyo Ally Mwai, Tadelle Dessie, Stephen Kemp, Sung Jong Oh and Heebal Kim

    BMC Genomics 2017 18:371

    Published on: 12 May 2017

  8. Research article

    The dynamics of early-state transcriptional changes and aggregate formation in a Huntington’s disease cell model

    Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by a CAG expansion in the Huntingtin (HTT) gene. Proteolytic cleavage of mutant huntingtin (Htt) protein with an expanded polyglutamine (poly...

    Martijn van Hagen, Diewertje G. E. Piebes, Wim C. de Leeuw, Ilona M. Vuist, Willeke M. C. van Roon-Mom, Perry D. Moerland and Pernette J. Verschure

    BMC Genomics 2017 18:373

    Published on: 12 May 2017

  9. Research article

    Discrimination of candidate subgenome-specific loci by linkage map construction with an S1 population of octoploid strawberry (Fragaria × ananassa)

    The strawberry, Fragaria × ananassa, is an allo-octoploid (2n = 8x = 56) and outcrossing species. Although it is the most widely consumed berry crop in the world, its complex genome structure has hindered its gen...

    Soichiro Nagano, Kenta Shirasawa, Hideki Hirakawa, Fumi Maeda, Masami Ishikawa and Sachiko N. Isobe

    BMC Genomics 2017 18:374

    Published on: 12 May 2017

  10. Research article

    Transcriptome analysis of the whitefly, Bemisia tabaci MEAM1 during feeding on tomato infected with the crinivirus, Tomato chlorosis virus, identifies a temporal shift in gene expression and differential regulation of novel orphan genes

    Whiteflies threaten agricultural crop production worldwide, are polyphagous in nature, and transmit hundreds of plant viruses. Little is known how whitefly gene expression is altered due to feeding on plants i...

    Navneet Kaur, Wenbo Chen, Yi Zheng, Daniel K. Hasegawa, Kai-Shu Ling, Zhangjun Fei and William M. Wintermantel

    BMC Genomics 2017 18:370

    Published on: 11 May 2017

  11. Research article

    Genome-wide association study confirm major QTL for backfat fatty acid composition on SSC14 in Duroc pigs

    Fatty acid composition contributes importantly to meat quality and is essential to the nutritional value of the meat. Identification of genetic factors underlying levels of fatty acids can be used to breed for...

    Maren van Son, Eli Gjerlaug Enger, Harald Grove, Roger Ros-Freixedes, Matthew P. Kent, Sigbjørn Lien and Eli Grindflek

    BMC Genomics 2017 18:369

    Published on: 11 May 2017

  12. Research article

    Integrated mRNA and microRNA transcriptome variations in the multi-tepal mutant provide insights into the floral patterning of the orchid Cymbidium goeringii

    Cymbidium goeringii is a very famous traditional orchid plant in China, which is well known for its spectacular and diverse flower morphology. In particular, the multi-tepal mutants ha...

    Fengxi Yang, Genfa Zhu, Zhen Wang, Hailin Liu, Qingquan Xu, Dan huang and Chaoyi Zhao

    BMC Genomics 2017 18:367

    Published on: 11 May 2017

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