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  1. In this work, a novel isatin-Schiff base L2 had been synthesized through a simple reaction between isatin and 2-amino-5-methylthio-1,3,4-thiadiazole. The produced Schiff base L2 was then subjected to a hydroth...

    Authors: Heba E. Saad, Gaber M. Abu El-Reash, Mohamed gaber, Mohamed A. Hashem, Yasmeen G. Abou El-Reash, Nuha Y. Elamin, Mohamed R. Elamin and Yusif S. El-Sayed
    Citation: BMC Genomics 2024 25:162
  2. Studies have confirmed that Infectious bovine rhinotracheitis virus (IBRV) infection induces mitochondrial damage. MicroRNAs (miRNAs) are a class of noncoding RNA molecules, which are involved in various biolo...

    Authors: Yingcai Ma, Xueping Guo, Qin He, Lu Liu, Zelong Li, Xiaomin Zhao, Wenxi Gu, Qi Zhong, Na Li, Gang Yao and Xuelian Ma
    Citation: BMC Genomics 2024 25:158
  3. Campylobacter spp. is the most frequent cause of bacterial food-borne gastroenteritis and a high priority antibiotic resistant bacterium according to the World Health Organization (WHO). European monitoring of th...

    Authors: Michael Zarske, Huong Quynh Luu, Carlus Deneke, Marie-Theres Knüver, Maja Thieck, Ha Thi Thu Hoang, Nancy Bretschneider, Ngoc Thi Pham, Ingrid Huber and Kerstin Stingl
    Citation: BMC Genomics 2024 25:156
  4. Significant differences in immune responses, prevalence or susceptibility of diseases and treatment responses have been described between males and females. Despite this, sex-differentiation analysis of the ge...

    Authors: Collins K. Boahen, Hannah Abee, Isis Ricaño Ponce, Leo A. B. Joosten, Mihai G. Netea and Vinod Kumar
    Citation: BMC Genomics 2024 25:154
  5. The accurate prediction of genomic breeding values is central to genomic selection in both plant and animal breeding studies. Genomic prediction involves the use of thousands of molecular markers spanning the ...

    Authors: Vanda M. Lourenço, Joseph O. Ogutu, Rui A.P. Rodrigues, Alexandra Posekany and Hans-Peter Piepho
    Citation: BMC Genomics 2024 25:152
  6. The mediator complex subunits (MED) constitutes a multiprotein complex, with each subunit intricately involved in crucial aspects of plant growth, development, and responses to stress. Nevertheless, scant repo...

    Authors: Le Liang, Dong Wang, Dongmei Xu, Jiachang Xiao, Wen Tang, Xueping Song, Guofeng Yu, Zongxu Liang, Minghui Xie, Zeping Xu, Bo Sun, Yi Tang, Zhi Huang, Yunsong Lai and Huanxiu Li
    Citation: BMC Genomics 2024 25:149
  7. Captivity and artificial food provision are common conservation strategies for the endangered golden snub-nosed monkey (Rhinopithecus roxellana). Anthropogenic activities have been reported to impact the fitness ...

    Authors: Xuanzhen Liu, Jianqiu Yu, Zongjin Huan, Mei Xu, Ting Song, Ruilin Yang, Wei Zhu and Jianping Jiang
    Citation: BMC Genomics 2024 25:148
  8. Diachasmimorpha longicaudata is a hymenopteran fruit fly endoparasitoid. Females of this species find their hosts for oviposition by using complex sensorial mechanisms in response to physical and chemical stimuli...

    Authors: Juan P. Wulff, Lucila M. Traverso, Jose M. Latorre-Estivalis, Diego F. Segura and Silvia B. Lanzavecchia
    Citation: BMC Genomics 2024 25:147
  9. Environmental monitoring of bacterial pathogens is critical for disease control in coastal marine ecosystems to maintain animal welfare and ecosystem function and to prevent significant economic losses. This r...

    Authors: Neža Orel, Eduard Fadeev, Gerhard J. Herndl, Valentina Turk and Tinkara Tinta
    Citation: BMC Genomics 2024 25:146
  10. Schizothorax o’connori is an endemic fish distributed in the upper and lower reaches of the Yarlung Zangbo River in China. It has experienced a fourth round of whole gene replication events and is a good model fo...

    Authors: Kuo Gao, Zhi He, Jinxin Xiong, Qiqi Chen, Bolin Lai, Fei Liu, Ping Chen, Mingqiang Chen, Wenjie Luo, Junjie Huang, Wenxiang Ding, Haochen Wang, Yong Pu, Li Zheng, Yuanyuan Jiao, Mingwang Zhang…
    Citation: BMC Genomics 2024 25:145
  11. The cation/proton antiporter (CPA) superfamily plays a crucial role in regulating ion homeostasis and pH in plant cells, contributing to stress resistance. However, in potato (Solanum tuberosum L.), systematic id...

    Authors: Jintao Liu, Dianjue Li, Jing Wang, Qian Wang, Xiao Guo, Qi Fu, Philip Kear, Guangtao Zhu and Xiaohui Yang
    Citation: BMC Genomics 2024 25:144
  12. Whole-exome sequencing (WES) is widely used to diagnose complex genetic diseases and rare conditions. The implementation of a robust and effective quality control system for sample identification and tracking ...

    Authors: Yong Huang, Yuanyuan Xiao, Shengqiu Qu, Jiaming Xue, Lin Zhang, Li Wang and Weibo Liang
    Citation: BMC Genomics 2024 25:142
  13. Schizochytrium limacinum holds significant value utilized in the industrial-scale synthesis of natural DHA. Nitrogen-limited treatment can effectively increase the content of fatty acids and DHA, but there is cur...

    Authors: Duo Chen, Jing Chen, Rongchun Dai, Xuehai Zheng, Yuying Han, Youqiang Chen and Ting Xue
    Citation: BMC Genomics 2024 25:141
  14. Fish scales are typical products of biomineralization and play an important role in the adaptation of fish to their environment. The Gymnocypris przewalskii scales are highly specialized, with scales embedded in ...

    Authors: Baoke Xu, Yanrong Cui, Linlin A., Haichen Zhang, Qinghua Ma, Fulei Wei and Jian Liang
    Citation: BMC Genomics 2024 25:140
  15. CircRNAs are a class of noncoding RNAs with tissue- and development-specific expression characteristics. In many mammals, primordial follicle development begins in the embryonic stage. However, the study of ci...

    Authors: Xiangyan Wang, Yan Zhang, Jianjie Yu, Yabo Ma, Yaxiu Xu, Jiaqi Shi, Zhipeng Qi and Xinfeng Liu
    Citation: BMC Genomics 2024 25:139
  16. Spermatogonial stem cells (SSCs) are the foundation cells for continual spermatogenesis and germline regeneration in mammals. SSC activities reside in the undifferentiated spermatogonial population, and curren...

    Authors: Shuang Li, Rong-Ge Yan, Xue Gao, Zhen He, Shi-Xin Wu, Yu-Jun Wang, Yi-Wen Zhang, Hai-Ping Tao, Xiao-Na Zhang, Gong-Xue Jia and Qi-En Yang
    Citation: BMC Genomics 2024 25:138
  17. Microbial remediation of heavy metal polluted environment is ecofriendly and cost effective. Therefore, in the present study, Shewanella putrefaciens stain 4H was previously isolated by our group from the activat...

    Authors: Yajun Cai, Xu Chen, Hanghang Qi, Fantong Bu, Muhammad Shaaban and Qi-An Peng
    Citation: BMC Genomics 2024 25:136
  18. Pseudogenes have been implicated for their role in regulating cellular differentiation and organismal development. However, their role in promoting cancer-associated differentiation has not been well-studied. ...

    Authors: Govada Pravallika and Ramalingam Rajasekaran
    Citation: BMC Genomics 2024 25:135
  19. Cluster heatmaps are widely used in biology and other fields to uncover clustering patterns in data matrices. Most cluster heatmap packages provide utility functions to divide the dendrograms at a certain leve...

    Authors: Feiling Feng, Qiaonan Duan, Xiaoqing Jiang, Xiaoming Kao and Dadong Zhang
    Citation: BMC Genomics 2024 25:134
  20. WD40 proteins, which are highly prevalent in eukaryotes, play important roles in plant development and stress responses. However, systematic identification and exploration of WD40 proteins in tobacco have not ...

    Authors: Lijun Meng, Huan Su, Zechao Qu, Peng Lu, Jiemeng Tao, He Li, Jianfeng Zhang, Wei Zhang, Nan Liu, Peijian Cao and Jingjing Jin
    Citation: BMC Genomics 2024 25:133
  21. The U-box gene family encodes E3 ubiquitin ligases involved in plant hormone signaling pathways and abiotic stress responses. However, there has yet to be a comprehensive analysis of the U-box gene family in maiz...

    Authors: Yongle Liu, Changgen Li, Aokang Qin, Wenli Deng, Rongrong Chen, Hongyang Yu, Yihua Wang, Jianbo Song and Liming Zeng
    Citation: BMC Genomics 2024 25:132
  22. Exploring the hypoxia adaptation mechanism of Tibetan chicken is of great significance for revealing the survival law of Tibetan chicken and plateau animal husbandry production. To investigate the hypoxia adap...

    Authors: Mingming Xue, Runjie Yu, Lixian Yang, Fuyin Xie, Meiying Fang and Qiguo Tang
    Citation: BMC Genomics 2024 25:131
  23. Circadian rhythm is crucial to the function of the immune system. Disorders of the circadian rhythm can contribute to inflammatory diseases such as Ulcerative colitis (UC). This Mendelian Randomization (MR) an...

    Authors: Mengfen Huang, Yuan Wu, Yiting Li, Xueru Chen, Jieni Feng, Zuming Li, Jiqiang Li, Jiankun Chen, Yue Lu and Yan Feng
    Citation: BMC Genomics 2024 25:130
  24. Lipid metabolism plays a pivotal role in asthma pathogenesis. However, a comprehensive analysis of the importance of lipid metabolism-related genes (LMRGs) in regulating the immune microenvironment in asthma r...

    Authors: Yuanmin Jia, Haixia Wang, Bin Ma, Zeyi Zhang, Jingjing Wang, Jin Wang and Ou Chen
    Citation: BMC Genomics 2024 25:129
  25. The NAC TF family is widely involved in plant responses to various types of stress. Red clover (Trifolium pratense) is a high-quality legume, and the study of NAC genes in red clover has not been comprehensive. T...

    Authors: Zicheng Wang, Zirui Chen, Yuchen Wu, Meiqi Mu, Jingwen Jiang, Wanting Nie, Siwen Zhao, Guowen Cui and Xiujie Yin
    Citation: BMC Genomics 2024 25:128
  26. Copy-number variations (CNVs), which refer to deletions and duplications of chromosomal segments, represent a significant source of variation among individuals, contributing to human evolution and being implic...

    Authors: Kun Xie, Xiaojun Ge, Haque A.K. Alvi, Kang Liu, Jianfeng Song and Qiang Yu
    Citation: BMC Genomics 2024 25:126
  27. Diabetic foot ulcer (DFU) is one of the most common and severe complications of diabetes, with vascular changes, neuropathy, and infections being the primary pathological mechanisms. Glutamine (Gln) metabolism...

    Authors: Hongshuo Shi, Xin Yuan, Xiao Yang, Renyan Huang, Weijing Fan and Guobin Liu
    Citation: BMC Genomics 2024 25:125
  28. Single-cell transcriptomics provides means to study cell populations at the level of individual cells. In leukocyte biology this approach could potentially aid the identification of subpopulations and function...

    Authors: Matilda Maxwell, Robert Söderlund, Sonja Härtle and Eva Wattrang
    Citation: BMC Genomics 2024 25:124
  29. Haloxylon ammodendron holds significance as an ecological plant, showcasing remarkable adaptability to desert conditions, halophytic environments, and sand fixation. With its potential for carbon sequestration, i...

    Authors: Lulu Yang, Jia Liu, Wenjun Guo, Zehan Zheng, Yafei Xu, Houjun Xia and Tian Xiao
    Citation: BMC Genomics 2024 25:123
  30. Cancers exhibit complex transcriptomes with aberrant splicing that induces isoform-level differential expression compared to non-diseased tissues. Transcriptomic profiling using short-read sequencing has utili...

    Authors: Saranga Wijeratne, Maria E. Hernandez Gonzalez, Kelli Roach, Katherine E. Miller, Kathleen M. Schieffer, James R. Fitch, Jeffrey Leonard, Peter White, Benjamin J. Kelly, Catherine E. Cottrell, Elaine R. Mardis, Richard K. Wilson and Anthony R. Miller
    Citation: BMC Genomics 2024 25:122
  31. To comprehensively understand the characteristics of the GH3 gene family in tea plants (Camellia sinensis), we identified 17 CsGH3 genes and analyzed their physicochemical properties, phylogenetic relationships, ...

    Authors: Xinge Wang, Chunyu Jia, Lishuang An, Jiangyan Zeng, Aixia Ren, Xin Han, Yiqing Wang and Shuang Wu
    Citation: BMC Genomics 2024 25:120
  32. Organisms from many distinct evolutionary lineages acquired the capacity to enter a dormant state in response to environmental conditions incompatible with maintaining normal life activities. Most studied orga...

    Authors: Tamar Hashimshony, Liron Levin, Andreas C. Fröbius, Nitsan Dahan, Vered Chalifa-Caspi, Reini Hamo, Oshri Gabai-Almog, Idit Blais, Yehuda G. Assaraf and Esther Lubzens
    Citation: BMC Genomics 2024 25:119
  33. Conifers are long-lived and slow-evolving, thus requiring effective defences against their fast-evolving insect natural enemies. The copy number variation (CNV) of two key acetophenone biosynthesis genes Ugt5/Ugt...

    Authors: Tin Hang Hung, Ernest T. Y. Wu, Pauls Zeltiņš, Āris Jansons, Aziz Ullah, Nadir Erbilgin, Joerg Bohlmann, Jean Bousquet, Inanc Birol, Sonya M. Clegg and John J. MacKay
    Citation: BMC Genomics 2024 25:118
  34. In cellular activities, essential proteins play a vital role and are instrumental in comprehending fundamental biological necessities and identifying pathogenic genes. Current deep learning approaches for pred...

    Authors: Chen Ye, Qi Wu, Shuxia Chen, Xuemei Zhang, Wenwen Xu, Yunzhi Wu, Youhua Zhang and Yi Yue
    Citation: BMC Genomics 2024 25:117
  35. Here we describe a new public pharmacogenetic (PGx) annotation database of a large (n = 3,202) and diverse biospecimen collection of 1000 Genomes Project cell lines and DNAs. The database is searchable with a use...

    Authors: N. Gharani, G. Calendo, D. Kusic, J. Madzo and L. Scheinfeldt
    Citation: BMC Genomics 2024 25:116
  36. Short tandem repeats (STRs) are widely distributed across the human genome and are associated with numerous neurological disorders. However, the extent that STRs contribute to disease is likely under-estimated...

    Authors: Jinfeng Lu, Camilo Toro, David R. Adams, Cristiane Araujo Martins Moreno, Wan-Ping Lee, Yuk Yee Leung, Mathew B. Harms, Badri Vardarajan and Erin L. Heinzen
    Citation: BMC Genomics 2024 25:115
  37. Theaceae, comprising 300 + species, holds significance in biodiversity, economics, and culture, notably including the globally consumed tea plant. Stewartia gemmata, a species of the earliest diverging tribe Stew...

    Authors: Daliang Liu, Zhihan Zhang, Yanlin Hao, Mengge Li, Houlin Yu, Xingruo Zhang, Haoyang Mi, Lin Cheng and Yiyong Zhao
    Citation: BMC Genomics 2024 25:114
  38. The corpora allata-corpora cardiaca (CA-CC) is an endocrine gland complex that regulates mosquito development and reproduction through the synthesis of juvenile hormone (JH). Epoxidase (Epox) is a key enzyme in t...

    Authors: Zhi Qi, Kayvan Etebari, Marcela Nouzova, Fernando G. Noriega and Sassan Asgari
    Citation: BMC Genomics 2024 25:113
  39. Auxin transcription factor (ARF) is an important transcription factor that transmits auxin signals and is involved in plant growth and development as well as stress response. However, genome-wide identificatio...

    Authors: Ming-jun Zhang, Ying-yu Xue, Shuang Xu, Xuan-ru Jin and Xing-chu Man
    Citation: BMC Genomics 2024 25:112
  40. Wohlfahrtia magnifica is an obligatory parasite that causes myiasis in several warm-blooded vertebrates. Adult females deposit the first-stage larvae directly onto wounds or natural body orifices (e.g., genitalia...

    Authors: Zhipeng Jia, Surong Hasi, Deng Zhan, Claus Vogl and Pamela A. Burger
    Citation: BMC Genomics 2024 25:111
  41. B-box (BBX) family is a class of zinc finger transcription factors (TFs) that play essential roles in regulating plant growth, development, as well as abiotic stress. However, no systematic analysis of BBX genes ...

    Authors: Shuxia Li, Shuaiqi Guo, Xueqin Gao, Xiaotong Wang, Yaling Liu, Jing Wang, Xiaohong Li, Jinqing Zhang and Bingzhe Fu
    Citation: BMC Genomics 2024 25:110
  42. Despite the many cheap and fast ways to generate genomic data, good and exact genome assembly is still a problem, with especially the repeats being vastly underrepresented and often misassembled. As short read...

    Authors: Ludwig Mann, Kristin Balasch, Nicola Schmidt and Tony Heitkam
    Citation: BMC Genomics 2024 25:109
  43. Diabetes cell replacement therapy has the potential to be transformed by human pluripotent stem cell-derived β cells (SC-β cells). However, the precise identity of SC-β cells in relationship to primary fetal a...

    Authors: Mason D. Schmidt, Matthew Ishahak, Punn Augsornworawat and Jeffrey R. Millman
    Citation: BMC Genomics 2024 25:105

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