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  1. Insect metamorphosis from larvae to pupae is one of the most important stages of insect life history. Relatively comprehensive information related to gene transcription profiles during lepidopteran metamorphos...

    Authors: Xinxin Gao, Jihong Zhang, Peipei Wu, Ruihao Shu, Huan Zhang, Qilian Qin and Qian Meng
    Citation: BMC Genomics 2022 23:591
  2. Carcass traits are important in pig breeding programs for improving pork production. Understanding the genetic variants underlies complex phenotypes can help explain trait variation in pigs. In this study, we ...

    Authors: Rongrong Ding, Zhanwei Zhuang, Yibin Qiu, Xingwang Wang, Jie Wu, Shenping Zhou, Donglin Ruan, Cineng Xu, Linjun Hong, Ting Gu, Enqin Zheng, Gengyuan Cai, Wen Huang, Zhenfang Wu and Jie Yang
    Citation: BMC Genomics 2022 23:590
  3. In the life history of Daphnia, the reproductive mode of parthenogenesis and sexual reproduction alternate in aquatic ecosystem, which are often affected by environmental and genetic factors. Recently, the sex-bi...

    Authors: Ziyan Wang, Feiyun Zhang, Qide Jin, Yeping Wang, Wenping Wang and Daogui Deng
    Citation: BMC Genomics 2022 23:589
  4. The cardiovascular developmental process is a tightly regulated network involving multiple genes. The current understanding of the molecular mechanism behind cardiovascular development is insufficient and requ...

    Authors: Chune Zhou, Wei Zhao, Shuqiang Zhang, Junguo Ma, Yousef Sultan and Xiaoyu Li
    Citation: BMC Genomics 2022 23:587
  5. Porcine Epidemic Diarrhea Virus (PEDV) is a coronavirus that seriously affects the swine industry. MicroRNAs and long noncoding RNAs are two relevant non-coding RNAs (ncRNAs) class and play crucial roles in a ...

    Authors: Xiaojie Shi, Qi Zhang, Jingjing Wang, Yuting Zhang, Yuchao Yan, Yi Liu, Naling Yang, Quanqiong Wang and Xingang Xu
    Citation: BMC Genomics 2022 23:586
  6. Quantitative real time PCR (qPCR) is a powerful tool to evaluate mRNA expression level. However, reliable qPCR results require normalization with validated reference gene(s). In this study, we investigated sta...

    Authors: Jeongah Song, Jeonghee Cho, Jeongsik Park and Jeong Ho Hwang
    Citation: BMC Genomics 2022 23:585
  7. Mitochondrial genomes are the most sequenced genomes after bacterial and fungal genomic DNA. However, little information on mitogenomes is available for multiple metazoan taxa, such as Culicoides, a globally dist...

    Authors: Yoamel Milián-García, Christopher A. Hempel, Lauren A. A. Janke, Robert G. Young, Tara Furukawa-Stoffer, Aruna Ambagala, Dirk Steinke and Robert H. Hanner
    Citation: BMC Genomics 2022 23:584
  8. Patatin-like phospholipase domain containing 5 (PNPLA5) is a newly-discovered lipase. Although the PNPLA family plays critical roles in diverse biological processes, the biological functions of PNPLA5 mostly u...

    Authors: Zhi-Guo Liu, Yan-Qing Hu, Kui Li, Yu-Lian Mu and Tian-Wen Wu
    Citation: BMC Genomics 2022 23:583
  9. Exome sequencing is becoming a routine in health care, because it increases the chance of pinpointing the genetic cause of an individual patient's condition and thus making an accurate diagnosis. It is importa...

    Authors: Vera Belova, Anna Shmitko, Anna Pavlova, Robert Afasizhev, Valery Cheranev, Anastasia Tabanakova, Natalya Ponikarovskaya, Denis Rebrikov and Dmitriy Korostin
    Citation: BMC Genomics 2022 23:582
  10. High temperature induces early bolting in lettuce (Lactuca sativa L.), which affects both quality and production. However, the molecular mechanism underlying high temperature-induced bolting is still limited.

    Authors: Jinghong Hao, Junwei Yang, Xiaofeng Liu, Gaoyang Pan, Yunfeng Li, Xiaolan Zhang, Yingyan Han, Shuangxi Fan and Zhaoyang Zhou
    Citation: BMC Genomics 2022 23:580
  11. Sequencing viruses in many specimens is hindered by excessive background material from hosts, microbiota, and environmental organisms. Consequently, enrichment of target genomic material is necessary for pract...

    Authors: Kevin S. Kuchinski, Jun Duan, Chelsea Himsworth, William Hsiao and Natalie A. Prystajecky
    Citation: BMC Genomics 2022 23:579
  12. Berberine hydrochloride is the main effective component of Coptis spp. used in Chinese herbal medicine and its underlying molecular mechanisms, responsible for inducing effects in crustacean species, are not f...

    Authors: Tian-heng Gao, Ming-ming Han, Hui Zhou, Chen-xi Zhu, Ying Yang, Zakaria Zuraini, Yan-Xia Guo and Qi-chen Jiang
    Citation: BMC Genomics 2022 23:578
  13. As a valuable medicinal plant, Rhodiola has a very long history of folk medicine used as an important adaptogen, tonic, and hemostatic. However, our knowledge of the chloroplast genome level of Rhodiola is limite...

    Authors: Kaihui Zhao, Lianqiang Li, Hong Quan, Junbo Yang, Zhirong Zhang, Zhihua Liao and Xiaozhong Lan
    Citation: BMC Genomics 2022 23:577
  14. Genetics studies in the porcine immune system have enhanced selection practices for disease resistance phenotypes and increased the efficacy of porcine models in biomedical research; however limited functional...

    Authors: Ryan J. Corbett, Andrea M. Luttman, Juber Herrera-Uribe, Haibo Liu, Nancy E. Raney, Jenna M. Grabowski, Crystal L. Loving, Christopher K. Tuggle and Catherine W. Ernst
    Citation: BMC Genomics 2022 23:575
  15. Echinoderms are established models in experimental and developmental biology, however genomic resources are still lacking for many species. Here, we present the draft genome of Ophioderma brevispinum, an emerging...

    Authors: Vladimir Mashanov, Denis Jacob Machado, Robert Reid, Cory Brouwer, Janice Kofsky and Daniel A. Janies
    Citation: BMC Genomics 2022 23:574
  16. Mammals rely on the circadian clock network to regulate daily systemic metabolism and physiological activities. The liver is an important peripheral organ in mammals, and it has a unique circadian rhythm regul...

    Authors: Yujia Chu, Jingjing Li, Lei Feng, Guoting Zhang, Hui Wu, Tinglei Jiang, Hui Wang and Jiang Feng
    Citation: BMC Genomics 2022 23:572
  17. Skeletal muscle tissue is among the largest organ systems in mammals, essential for survival and movement. Embryonic muscle development determines the quantity and quality of muscles after the birth of an indi...

    Authors: Jun’an Shi, Wendong Li, Anfang Liu, Lingtong Ren, Pusen Zhang, Ting Jiang, Yuqing Han and Lingbin Liu
    Citation: BMC Genomics 2022 23:571
  18. Saposhnikovia divaricata (Turcz.) Schischk. is a perennial herb whose dried roots are commonly used as a source of traditional medicines. To elucidate the organelle-genome-based phylogeny of Saposhnikovia species...

    Authors: Yang Ni, Jingling Li, Haimei Chen, Jingwen Yue, Pinghua Chen and Chang Liu
    Citation: BMC Genomics 2022 23:570
  19. To understand the dynamics of infectious diseases, genomic epidemiology is increasingly advocated, with a need for rapid generation of genetic sequences during outbreaks for public health decision making. Here...

    Authors: David F. Nieuwenhuijse, Anne van der Linden, Robert H. G. Kohl, Reina S. Sikkema, Marion P. G. Koopmans and Bas B. Oude Munnink
    Citation: BMC Genomics 2022 23:569
  20. Brassinosteroids (BRs) are a group of essential steroid hormones involved in diverse developmental and physiological processes in plants. The Brassinazole-resistant 1 (BZR1) transcription factors are key compo...

    Authors: Chunliu Zuo, Lan Zhang, Xinyue Yan, Xinyue Guo, Qing Zhang, Songyang Li, Yanling Li, Wen Xu, Xiaoming Song, Jinpeng Wang and Min Yuan
    Citation: BMC Genomics 2022 23:568
  21. Acer pseudosieboldianum is a kind of excellent color-leafed plants, and well known for its red leaves in autumn. At the same time, A. pseudosieboldianum is one of the native tree species in the northeast of China...

    Authors: Jia-Lin Li, Zhuo Weng, Xin-Yu Li, Bo Xu, Yu-Fu Gao and Li-Ping Rong
    Citation: BMC Genomics 2022 23:567
  22. The genus Verbascum L. (Scrophulariaceae) is distributed in Africa, Europe, and parts of Asia, with the Mediterranean having the most species variety. Several researchers have already worked on the phylogenetic a...

    Authors: Xiang Dong, Elijah Mbandi Mkala, Elizabeth Syowai Mutinda, Jia-Xin Yang, Vincent Okelo Wanga, Millicent Akinyi Oulo, Victor Omondi Onjolo, Guang-Wan Hu and Qing-Feng Wang
    Citation: BMC Genomics 2022 23:566
  23. Shrimp have the ability to accommodate viruses in long term, persistent infections without signs of disease. Endogenous viral elements (EVE) play a role in this process probably via production of negative-sens...

    Authors: Suparat Taengchaiyaphum, Prapatsorn Wongkhaluang, Kanchana Sittikankaew, Nitsara Karoonuthaisiri, Timothy W. Flegel and Kallaya Sritunyalucksana
    Citation: BMC Genomics 2022 23:565
  24. Past selection events left footprints in the genome of domestic animals, which can be traced back by stretches of homozygous genotypes, designated as runs of homozygosity (ROHs). The analysis of common ROH reg...

    Authors: Jan Berghöfer, Nadia Khaveh, Stefan Mundlos and Julia Metzger
    Citation: BMC Genomics 2022 23:564
  25. Type 2C protein phosphatase (PP2C) is a negative regulator of ABA signaling pathway, which plays important roles in stress signal transduction in plants. However, little research on the PP2C genes family of cucum...

    Authors: Guobin Zhang, Zeyu Zhang, Shilei Luo, Xia Li, Jian Lyu, Zeci Liu, Zilong Wan and Jihua Yu
    Citation: BMC Genomics 2022 23:563
  26. Transcriptome-wide association studies (TWASs) have shown great promise in interpreting the findings from genome-wide association studies (GWASs) and exploring the disease mechanisms, by integrating GWAS and e...

    Authors: Xiuyuan Jin, Liye Zhang, Jiadong Ji, Tao Ju, Jinghua Zhao and Zhongshang Yuan
    Citation: BMC Genomics 2022 23:562
  27. Mycobacterium tuberculosis presents several lineages each with distinct characteristics of evolutionary status, transmissibility, drug resistance, host interaction, latency, and vaccine efficacy. Whole genome seq...

    Authors: Beatrice Kemilembe Mutayoba, Michael Hoelscher, Norbert Heinrich, Moses L. Joloba, Eligius Lyamuya, Andrew Martin Kilale, Nyagosya Segere Range, Bernard James Ngowi, Nyanda Elias Ntinginya, Saidi Mwinjuma Mfaume, Amani Wilfred, Basra Doulla, Johnson Lyimo, Riziki Kisonga, Amri Kingalu, Jupiter Marina Kabahita…
    Citation: BMC Genomics 2022 23:561
  28. Cyclic nucleotide-gated ion channels (CNGCs) are calcium-permeable channels that participate in a variety of biological functions, such as signaling pathways, plant development, and environmental stress and stimu...

    Authors: Zhengying Lu, Guo Yin, Mao Chai, Lu Sun, Hengling Wei, Jie Chen, Yufeng Yang, Xiaokang Fu and Shiyun Li
    Citation: BMC Genomics 2022 23:560
  29. Plants synthesize metabolites to adapt to a continuously changing environment. Metabolite biosynthesis often occurs in response to the tissue-specific combinatorial developmental cues that are transcriptionall...

    Authors: Xiaoyang Gao, Qixuan Su, Jing Li, Wenjing Yang, Baolin Yao, Jiawei Guo, Shengying Li and Changning Liu
    Citation: BMC Genomics 2022 23(Suppl 1):559

    This article is part of a Supplement: Volume 23 Supplement 1

  30. Tetrodotoxin (TTX) is a deadly neurotoxin and usually accumulates in large amounts in the ovaries but is non-toxic or low toxic in the testis of pufferfish. The molecular mechanism underlying sexual dimorphism...

    Authors: Xue He, Hexing Wu, Yaping Ye, Xiaolin Gong and Baolong Bao
    Citation: BMC Genomics 2022 23:553
  31. The expression and biological functions of circular RNAs (circRNAs) in reproductive organs have been extensively reported. However, it is still unclear whether circRNAs are involved in sex change. To this end,...

    Authors: Zhi He, Zhijun Ma, Deying Yang, Qiqi Chen, Zhide He, Jiaxiang Hu, Faqiang Deng, Qian Zhang, Jiayang He, Lijuan Ye, Hongjun Chen, Liang He, Xiaoli Huang, Wei Luo, Shiyong Yang, Xiaobin Gu…
    Citation: BMC Genomics 2022 23:552
  32. In cold regions, low temperature is the main limiting factor affecting grape production. As an important breeding resource, V. amurensis Rupr. has played a crucial role in the discovery of genes which confer cold...

    Authors: Xiaolele Ma, Fangyuan Zhao, Kai Su, Hong Lin and Yinshan Guo
    Citation: BMC Genomics 2022 23:551
  33. The Qinba region is the transition region between Indica and Japonica varieties in China. It has a long history of Indica rice planting of more than 7000 years and is also a planting area for fine-quality Indi...

    Authors: Yu Zhang, Qiaoqiao He, Xixi Zhou, Shimao Zheng, Yewen Wang, Peijiang Li and Yuexing Wang
    Citation: BMC Genomics 2022 23:550
  34. Transcription factors (TFs) play important roles in plants. Among the major TFs, GATA plays a crucial role in plant development, growth, and stress responses. However, there have been few studies on the GATA g...

    Authors: Dili Lai, Xin Yao, Jun Yan, Anjing Gao, Hao Yang, Dabing Xiang, Jingjun Ruan, Yu Fan and Jianping Cheng
    Citation: BMC Genomics 2022 23:549
  35. Green-fleshed radish (Raphanus sativus L.) is an economically important root vegetable of the Brassicaceae family, and chlorophyll accumulates in its root tissues. It was reported that the basic helix-loop-helix ...

    Authors: Ruihua Wang, Yuanyuan Li, Minggang Gao, Min Han and Huilian Liu
    Citation: BMC Genomics 2022 23:548
  36. OSCA (hyperosmolality-gated calcium-permeable channel) is a calcium permeable cation channel protein that plays an important role in regulating plant signal transduction. It is involved in sensing changes in e...

    Authors: Shuang Miao, Fengshuo Li, Yang Han, Zhongtong Yao, Zeqian Xu, Xiuling Chen, Jiayin Liu, Yao Zhang and Aoxue Wang
    Citation: BMC Genomics 2022 23:547
  37. Population-scale expression profiling studies can provide valuable insights into biological and disease-underlying mechanisms. The availability of phenotypic traits is essential for studying clinical effects. ...

    Authors: Anna Niehues, Daniele Bizzarri, Marcel J.T. Reinders, P. Eline Slagboom, Alain J. van Gool, Erik B. van den Akker and Peter A.C. ’t Hoen
    Citation: BMC Genomics 2022 23:546
  38. Renal inflammation plays a crucial role during the progression of Chronic kidney disease (CKD), but there is limited research on hub genes involved in renal inflammation. Here, we aimed to explore the effects ...

    Authors: Jing Chen, Yuwei Liu, Shang Xia, Xujun Ye and Ling Chen
    Citation: BMC Genomics 2022 23:544
  39. The immune repertoires of mollusks beyond commercially important organisms such as the pacific oyster Crassostrea gigas or vectors for human pathogens like the bloodfluke planorb Biomphalaria glabrata are underst...

    Authors: Nicholas S. Kron
    Citation: BMC Genomics 2022 23:543
  40. Exposure to environmental mutagens increases the risk of cancer and genetic disorders. We used Duplex Sequencing (DS), a high-accuracy error-corrected sequencing technology, to analyze mutation induction acros...

    Authors: Danielle P. M. LeBlanc, Matthew Meier, Fang Yin Lo, Elizabeth Schmidt, Charles Valentine III, Andrew Williams, Jesse J. Salk, Carole L. Yauk and Francesco Marchetti
    Citation: BMC Genomics 2022 23:542
  41. Mymaridae is an ancient insect group and is a basal lineage of the superfamily Chalcidoidea. Species of Mymaridae have great potential for biological control. Anagrus nilaparvatae, a representative species of Mym...

    Authors: Ying Ma, Zixiao Guo, Liyang Wang, Bingyang Wang, Tingfa Huang, Bingjie Tang, Guren Zhang and Qiang Zhou
    Citation: BMC Genomics 2022 23:541

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