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Figure 2 | BMC Genomics

Figure 2

From: Evolution from a respiratory ancestor to fill syntrophic and fermentative niches: comparative genomics of six Geobacteraceae species

Figure 2

The pathways of energy metabolism conserved in the respiratory Geobacteraceae species. Shown are the pathways, based those characterized in G. sulfurreducens, for acetate activation and oxidation via the TCA cycle in the cytoplasm, for inner membrane oxidation of TCA cycle products coupled with electron and proton transport, and for ATP generation. The genes encoding the enzymes of these pathways and their conservation pattern in all of the Geobacteraceae genomes are given in see Additional file 7. The enzymes are colored black if there were orthologs for every subunit in all of the respiratory species. The asterisk indicates that malate dehydrogenase activity has been shown in D. acetoxidans, though genes for the enzyme were not found in the draft sequence of the genome. The pathway for electron transfer through the periplasm and out to the external electron acceptor is not well characterized in these species, and is represented here by the three cytochromes known to be required in vivo in G. sulfurreducens that are also conserved in all of the respiratory species.

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