Homologous analysis of EST clusters from human pituitaries. (A) 961 EST clusters were generated from fetal pituitary using software CAT 3.5 (Pangea) with default parameters, and classified as the known genes, known ESTs and novel ESTs by searching against public DNA and protein databases. Novel EST clusters indicated that no known human genes and ESTs in public databases shared identity with the ESTs. (B) Distribution of 2747 EST clusters from adult pituitary based on homology analysis. (C) Overlapping of EST clusters from fetal and adult pituitaries. Overlapping region indicates the numbers of EST clusters shared by both cDNA resources, while the other numbers represent EST clusters found only in fetal or adult cDNA libraries.