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Table 1 The first 20 known genes expressed highly in human pituitaries based on EST data

From: Identification of candidate genes for human pituitary development by EST analysis

Unigene No.

Gene name

Copies

%*

Fetal pituitary

Hs.1905

prolactin+#

312

9.46

Hs.119689

glycoprotein hormones, alpha +#

146

4.43

Hs.115352

growth hormone 1+#

48

1.46

Hs.274460

olfactory receptor 5V1#

48

1.46

Hs.195453

ribosomal protein S27+#

24

0.73

Hs.75415

beta-2-microglobulin+#

22

0.67

Hs.70312

cytochrome c oxidase 7A2+#

15

0.46

Hs.315164

hypothetical protein#

14

0.42

Hs.83484

sex determining region Y-box 4#

8

0.24

Hs.7917

DKFZP564K247 protein#

7

0.21

Hs.273385

guanine nucleotide binding protein alpha+#

7

0.21

Hs.165590

ribosomal protein S13#

7

0.21

Hs.131814

tankyrase#

7

0.21

Hs.173912

eukaryotic translation initiation factor+

6

0.18

Hs.119222

suppression of tumorigenicity 13+#

6

0.18

Hs.177530

ATP synthase+

5

0.15

Hs.177656

calmodulin 1+

5

0.15

Hs.241429

cDNA DKFZp586C1923#

5

0.12

Hs.330994

RAB9#

4

0.12

Hs.46328

fucosyltransferase 2#

4

0.12

Adult pituitary

Hs.115352

growth hormone 1+#

358

6.09

Hs.1905

prolactin+#

288

4.9

Hs.1897

proopiomelanocortin#

46

0.78

Hs.181165

eukaryotic translation elongation factor1#

45

0.77

Hs.273385

guanine nucleotide binding protein AS1+#

44

0.75

Hs.65149

growth hormone 2#

42

0.71

Hs.279789

glucose phosphate isomerase#

41

0.7

Hs.119689

glycoprotein hormones, alpha+#

37

0.63

Hs.77385

myosin, light polypeptide 6+#

30

0.51

Hs.278959

galanin-related peptide LOC51083#

25

0.43

Hs.247474

hypothetical protein FLJ21032#

21

0.36

Hs.180450

ribosomal protein S24#

20

0.34

Hs.155482

hydroxyacyl glutathione hydrolase#

19

0.32

Hs.76053

DEAD/H box polypeptide 5#

19

0.32

Hs.75360

carboxypeptidase E+#

18

0.31

Hs.112844

maternally expressed 3#

16

0.27

Hs.117950

phosphoribosylaminoimidazole carboxylase#

16

0.27

Hs.119598

ribosomal protein L3#

16

0.27

Hs.5464

skeletal muscle abundant protein#

16

0.27

Hs.179526

thioredoxin interacting protein #

15

0.26

  1. * Percentage of a given EST in all ESTs obtained from that of cDNA libraries.
  2. + The genes presented in the EST libraries of both fetal and adult pituitary.
  3. # Significant differences in gene expression (P < 0.05) between fetal and adult pituitaries http://igs-server.cnrs-mrs.fr.