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Table 1 The first 20 known genes expressed highly in human pituitaries based on EST data

From: Identification of candidate genes for human pituitary development by EST analysis

Unigene No. Gene name Copies %*
Fetal pituitary
Hs.1905 prolactin+# 312 9.46
Hs.119689 glycoprotein hormones, alpha +# 146 4.43
Hs.115352 growth hormone 1+# 48 1.46
Hs.274460 olfactory receptor 5V1# 48 1.46
Hs.195453 ribosomal protein S27+# 24 0.73
Hs.75415 beta-2-microglobulin+# 22 0.67
Hs.70312 cytochrome c oxidase 7A2+# 15 0.46
Hs.315164 hypothetical protein# 14 0.42
Hs.83484 sex determining region Y-box 4# 8 0.24
Hs.7917 DKFZP564K247 protein# 7 0.21
Hs.273385 guanine nucleotide binding protein alpha+# 7 0.21
Hs.165590 ribosomal protein S13# 7 0.21
Hs.131814 tankyrase# 7 0.21
Hs.173912 eukaryotic translation initiation factor+ 6 0.18
Hs.119222 suppression of tumorigenicity 13+# 6 0.18
Hs.177530 ATP synthase+ 5 0.15
Hs.177656 calmodulin 1+ 5 0.15
Hs.241429 cDNA DKFZp586C1923# 5 0.12
Hs.330994 RAB9# 4 0.12
Hs.46328 fucosyltransferase 2# 4 0.12
Adult pituitary
Hs.115352 growth hormone 1+# 358 6.09
Hs.1905 prolactin+# 288 4.9
Hs.1897 proopiomelanocortin# 46 0.78
Hs.181165 eukaryotic translation elongation factor1# 45 0.77
Hs.273385 guanine nucleotide binding protein AS1+# 44 0.75
Hs.65149 growth hormone 2# 42 0.71
Hs.279789 glucose phosphate isomerase# 41 0.7
Hs.119689 glycoprotein hormones, alpha+# 37 0.63
Hs.77385 myosin, light polypeptide 6+# 30 0.51
Hs.278959 galanin-related peptide LOC51083# 25 0.43
Hs.247474 hypothetical protein FLJ21032# 21 0.36
Hs.180450 ribosomal protein S24# 20 0.34
Hs.155482 hydroxyacyl glutathione hydrolase# 19 0.32
Hs.76053 DEAD/H box polypeptide 5# 19 0.32
Hs.75360 carboxypeptidase E+# 18 0.31
Hs.112844 maternally expressed 3# 16 0.27
Hs.117950 phosphoribosylaminoimidazole carboxylase# 16 0.27
Hs.119598 ribosomal protein L3# 16 0.27
Hs.5464 skeletal muscle abundant protein# 16 0.27
Hs.179526 thioredoxin interacting protein # 15 0.26
  1. * Percentage of a given EST in all ESTs obtained from that of cDNA libraries.
  2. + The genes presented in the EST libraries of both fetal and adult pituitary.
  3. # Significant differences in gene expression (P < 0.05) between fetal and adult pituitaries http://igs-server.cnrs-mrs.fr.