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Table 1 List of the top eight functional categories of DEGs, based on the protein annotations of the UniProt databases

From: Transcription and splicing regulation in human umbilical vein endothelial cells under hypoxic stress conditions by exon array

Rank

Terms

Count

%

P-value

1

Alternative splicing

381

24.1

1.3E-23

2

Nuclear protein

355

22.4

1.2E-29

3

Phosphorylation

312

19.7

3.0E-58

4

Metal-binding

191

12.1

8.8E-5

5

Nucleotide-binding

190

12.0

1.4E-23

6

Transferase

164

10.3

2.6E-16

7

ATP-binding

157

9.9

5.4E-22

8

DNA-binding

137

8.7

5.1E-5

  1. (Threshold of significance: P < 1 × 10-4, Fisher's exact test)