Developmental gene expression profiles of the human pathogen Schistosoma japonicum

BMC Genomics

Table 1 Number of upregulated genes in S. japonicum determined by ANOVA.

	Normalised Intensity/Median Intensity of All Stages
	2 fold		5 fold
Lifecycle Stage	Probes	Genes	Probes	Genes
Eggs	1312	931	136	103
Miracidia	399	306	195	162
Sporocysts	327	244	95	78
Cercariae	899	629	106	72
All Aquatic/Snail Stages	80	62	11	9
Lung Schistosomula	366	296	133	117
Juvenile Males	102	81	35	27
Juvenile Females	197	149	45	39
Adult Males Combined weeks 6–7	307	217	70	54
All Males Parasites + juvenile	79	62	21	16
Adult Females combined weeks 6–7	241	184	54	47
All Females Parasites + juvenile	138	106	47	42
Total	4447	3267 (1782)	948	766

The intensity for each development stage was normalised to the median intensity of all the developmental stages examined for each gene, thus providing a relative fold change. The number of probes or genes enriched 2- or 5-fold is presented. The 1782 value in parenthesis in the Total row, refers to the number of non-redundant genes enriched 2-fold or higher.

ISSN: 1471-2164