Table 2 Some of the highly enriched transcripts from the different developmental stages of S. japonicum.
From: Developmental gene expression profiles of the human pathogen Schistosoma japonicum
Lifecycle Stage | Probe | Nucleotide Description/Protein Homology | Fold Δ |
|---|---|---|---|
Egg | Contig7259 | /SJCHGC02876/aquaporin 9 | 100.91 |
| Â | Contig8558 | S. mansoni calcium-binding protein/calmodulin | 99.13 |
| Â | Contig7271 | S. mansoni anti-inflammatory protein 16/SJCHGC05573 | 49.15 |
| Â | Contig3014 | solute carrier family 37 (glycerol-3-phosphate transporter) | 2.35 |
| Â | Contig7936 | S. mansoni eukaryotic translation initiation factor 2 | 2.30 |
| Â | Contig4628 | A. thaliana dynamin-like protein 6 (ADL6). | 2.07 |
Miracidium | Contig1657 | ,/insulin-like peptide receptor ilp-r | 79.25 |
| Â | Contig714 | S. mansoni for Sm10 protein/dynein light chain 2 | 19.99 |
| Â | Contig7933 | S. mansoni calponin homolog,/SJCHGC02977 | 18.55 |
| Â | Contig5142 | solute carrier family 7 (cationic amino acid) | 16.25 |
| Â | Contig3311 | monocarboxylate transporter | 12.58 |
| Â | Contig8754 | cytochrome c oxidase subunit i | 2.76 |
| Â | Contig4272 | S. japonicum for serine-enzyme/---NA--- | 2.03 |
Sporocyst | Contig714 | S. mansoni for Sm10 protein/dynein light chain 2 | 79.73 |
| Â | Contig6889 | S. japonicum clone ZZZ32/plexin domain containing 2 | 27.99 |
| Â | Contig5142 | SJCHGC04289/solute carrier family 7 member 8 | 8.48 |
| Â | TC16140 | pyruvate kinase | 3.55 |
| Â | Contig8948 | ribosomal protein s14 | 3.02 |
| Â | Contig5652 | udp-glucose dehydrogenase | 2.95 |
| Â | Contig1610 | ribosomal protein l31 | 2.54 |
| Â | Contig6944 | leucine zipper-ef-hand containing transmembrane protein 1 | 2.02 |
Cercaria | Contig8837 | S. japonicum clone ZZD363/glutamine synthetase | 11.12 |
| Â | Contig5222 | S. japonicum thioredoxin,/mgc80314 protein | 8.73 |
| Â | Contig6136 | Canis familiaris endothelin B receptor/SJCHGC09785 | 7.27 |
| Â | Contig5932 | o-linked n-acetylglucosamine transferase | 4.13 |
| Â | Contig1574 | /NADH dehydrogenase subunit 5 [Strongyloides stercoralis] | 3.69 |
| Â | Contig7759 | S. japonicum cytochrome c oxidase 3 | 3.11 |
| Â | Contig7070 | actin binding1b | 2.71 |
| Â | Contig4282 | dynamin 1 | 2.49 |
| Â | Contig4204 | /cytochrome c oxidase subunit III [Siphonodentalium lobatum] | 2.43 |
| Â | Contig690 | /Cytochrome C oxidase, mono-heme subunit [Shewanella denitrificans ] | 2.34 |
| Â | Contig8895 | S. japonicum actin mRNA, complete cds/actin | 2.32 |
| Â | Contig6947 | amp-activated protein kinase | 2.26 |
| Â | Contig7330 | S. japonicum cytochrome C oxidase copper chaperone | 2.23 |
| Â | Contig3578 | protein phosphatase 1b magnesium-beta isoform | 2.12 |
| Â | Contig1640 | esterase a | 2.06 |
| Â | Contig1629 | histone deacetylase 3 | 2.06 |
| Â | TC17311 | glycogen synthase kinase 3 alpha | 2.00 |
Lung Schistosomula | Contig4998 | /ef-hand calcium binding protein | 9.68 |
| Â | Contig7933 | S. mansoni calponin homolog,/SJCHGC02977 | 5.37 |
| Â | Contig7060 | S. japonicum polyubiquitin (UBC) | 4.23 |
| Â | Contig6917 | secretory carrier membrane protein 2 | 3.90 |
| Â | TC17030 | centrin 3 | 3.87 |
| Â | Contig6538 | S. japonicum for paramyosin,/paramyosin | 3.27 |
| Â | Contig7916 | calreticulin | 2.46 |
| Â | Contig6517 | S. mansoni heat shock protein 70 | 2.40 |
| Â | TC14572 | synaptojanin 1 | 2.05 |
Juvenile Male | TC13825 | SJCHGC01839/glioma pathogenesis-related protein | 8.82 |
| Â | Contig4272 | S. japonicum for serine-enzyme/---NA--- | 5.00 |
| Â | Contig8395 | S. mansoni 200 kDa surface protein,/SJCHGC09596/ | 3.30 |
| Â | Contig8253 | thymosin beta | 2.79 |
| Â | Contig8718 | glycosyltransferase 1 domain containing 1 | 2.37 |
| Â | Contig8946 | S. japonicum fatty acid binding protein | 2.21 |
| Â | Contig8017 | annexin a7 | 2.02 |
Juvenile Female | TC9476 | putative ferredoxin reductase; Mesorhizobium loti/ | 58.52 |
| Â | Contig7517 | SJCHGC00284/epididymal secretory protein e1 | 10.47 |
| Â | Contig8731 | S. japonicum clone ZZD10/SJCHGC06317/cd63 antigen | 6.36 |
| Â | Contig5142 | solute carrier family 7 (cationic amino acidy+ system)member 8 | 5.27 |
| Â | Contig2104 | valosin containing protein | 2.57 |
| Â | Contig7465 | adenylosuccinate synthase like 1 | 2.49 |
|  | TC11333 | DNA mismatch repair protein MSH2 – African clawed frog | 2.29 |
| Â | Contig5394 | novel transmembrane amino acid transporter protein | 2.26 |
| Â | Contig3981 | thioredoxin peroxidase | 2.09 |
Adult Male | Contig7688 | S. japonicum dynein light chain 3 (DLC3) | 13.31 |
| Â | Contig7484 | S. japonicum clone ZZZ342/cd38 antigen | 10.26 |
| Â | Contig4443 | solute carrier family 1 (glial high affinity glutamate transporter) | 6.01 |
| Â | Contig8927 | S. japonicum clone ZZZ66/SJCHGC00511/cathepsin f | 4.85 |
| Â | Contig7921 | S. japonicum cathepsin B endopeptidase/cathepsin b | 4.57 |
| Â | Contig4208 | H. sapiens clone RP11-124P23/SJCHGC05752/paramyosin | 4.27 |
| Â | Contig4684 | /SJCHGC01577/annexin 5 | 3.75 |
| Â | Contig7122 | S. mansoni tegumental antigen (Sm8)/SJCHGC00665 | 3.54 |
| Â | Contig8822 | S. japonicum actin | 3.30 |
| Â | Contig8859 | myosin heavy chain | 3.24 |
| Â | TC7585 | fimbrin {S. mansoni}, complete | 3.19 |
| Â | TC17273 | alkaline phosphatase | 3.18 |
| Â | Contig2404 | sperm associated antigen 6 | 2.49 |
| Â | Contig8527 | solute carrier family 2 (facilitated glucose transporter)member 5 | 2.37 |
| Â | Contig6302 | clathrin coat assembly protein ap19 | 2.31 |
| Â | Contig1963 | S. mansoni glutathione S-transferase | 2.20 |
Adult Female | Contig5142 | SJCHGC04289/solute carrier family 7 member 8 | 11.85 |
| Â | Contig8731 | S. japonicum clone ZZD10/SJCHGC06317/cd63 antigen | 9.39 |
| Â | Contig7312 | /SJCHGC05381/transmembrane 9 superfamily member 2 | 5.40 |
| Â | Contig7830 | /SJCHGC02408/ferric-chelate reductase 1 | 3.94 |
| Â | TC8025 | ribosomal protein s27-like | 3.74 |
| Â | TC11576 | ribosomal protein l37 | 3.59 |
| Â | TC7041 | ribosomal protein l7a | 3.32 |
| Â | Contig7888 | folate-binding protein 1 | 3.31 |
| Â | TC14195 | 60s ribosomal protein l39 | 3.25 |
| Â | Contig8147 | S. mansoni receptor for activated PKC | 3.06 |
| Â | Contig2978 | microtubule associated serine threonine kinase-like | 2.69 |
|  | TC11333 | DNA mismatch repair protein MSH2 – African clawed frog | 2.60 |
| Â | Contig7235 | calmodulin | 2.52 |
| Â | TC7616 | 60s acidic ribosomal protein p2 | 2.46 |
| Â | Contig8062 | phosphogluconate dehydrogenase | 2.36 |
| Â | Contig1324 | copper chaperone | 2.35 |
| Â | TC12062 | glucosidase 1 | 2.15 |
| Â | Contig3791 | asparagine-linked glycosylation 6 homolog | 2.10 |
| Â | Contig8420 | arginase ii | 2.03 |