Figure 4

Hierarchical clustering analysis of the genes identified by functional profiling in iron deficiency under diverse growth conditions. Genes identified in iron deficiency were compared for functional requirement across different conditions from previously-published studies. Clusters contain genes with similar or opposite responses in these conditions to BPS treatment. Enriched GO biological processes for each cluster are indicated with corresponding hypergeometric p-values. Growth at pH 8 showed the closest similarity in genes to BPS treatment, with the majority of required genes associated to intracellular transport, but at the same time showed opposite requirements for a subgroup of genes also associated with this process.