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Table 2 Gene Ontology enrichment by biological process and cellular localization of genes identified by functional profiling

From: Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae

BIOLOGICAL PROCESS

CELLULAR COMPONENT

Category

p-value1

# genes2

Category

p-value1

# genes2

Transport

1.87 E-14

53

Endosome

5.24 E-10

11

Organelle organization and biogenesis

2.44 E-12

41

Peroxisome

5.11 E-07

9

Peroxisome organization and biogenesis

6.98 E-12

11

Cytoplasm

3.94 E-06

73

Intracellular protein transport

3.11 E-11

32

Peroxisomal membrane

6.98 E-06

5

Protein transport

6.79 E-10

33

Intracellular

1.16 E-04

98

Protein-peroxisome targeting

4.41 E-09

7

Cell

1.75 E-04

102

Protein targeting

4.99 E-09

22

AP-3 adaptor complex

3.76 E-03

2

Cytoplasm organization and biogenesis

1.82 E-08

41

Vacuolar membrane

6.58 E-03

5

Vacuole organization and biogenesis

6.98 E-07

14

Hydrogen-translocating V-type ATPase complex

7.16 E-03

3

Protein-vacuolar targeting

1.90 E-06

10

Membrane

7.28 E-03

28

  1. 1Calculated from hypergeometric distribution P < 0.01
  2. 2Number of identified genes in the Gene Ontology (GO) category
  3. Enriched categories were identified using Funspec; see Additional file 4 for complete tables.