Figure 5
From: A signature-based method for indexing cell cycle phase distribution from microarray profiles
A model of tumors with different cell cycle phase distributions. Oncogenic events perturb the cell cycle each in their unique way, which alters cell cycle phase distribution as well as proliferation rate. High proliferative tumors grow rapidly and produce large number of cycling cells, but exceptions exist at a low probability. CCS can characterize them under consideration of cycling and non-cycling cells.