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Table 5 List of three-copy genes overexpressed in Ts1Cje mice and differentially expressed during cerebellar development.

From: Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development

 

Trisomy effect

Developmental effect

 

P0

P3

P7

P10

P0 → P3

P0 → P7

P0 → P10

Girk2

1.21

1.40

1.31

1.29

1.50

3.31

3.11

Olig1

1.47

ns

1.34

ns

1.88

ns

ns

Dscam

ns

1.41

ns

ns

0.76

ns

ns

  1. Expression ratio between trisomic and euploid mice (trisomy effect) and betwen two time points (development effect). (ANOVA, α = 5%). NS: not significant.
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BMC Genomics

ISSN: 1471-2164

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