Skip to main content

Table 6 List of genes differentially expressed in the external granule cell layer of Ts1Cje mice at P0 (q < 0.05)

From: Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development

SYMBOL

Ratio

p-value

q-value

Chr

GO biological process category

1810007M14Rik

1.53

0,000

0,004

16

Regulation of transcription

2400009B08Rik

0.8

0

0,029

8

 

2610039C10Rik

1.5

0,000

0,038

16

 

Atp5o

1.27

0,000

0,001

16

ATP biosynthetic process, H+ transport

B3galt5

1.4

0,000

0,014

16

Protein amino acid glycosylation

Brwd1

1.35

0,000

0,036

16

Regulation of transcription

Cbr1

1.32

0,000

0,007

16

Carbonyl reductase (NADPH) activity

Cdca7l

0.46

0

0

12

Cell proliferation, transcription

Chaf1b

1.43

0,000

0,036

16

Cell cycle, DNA replication, Transcrip tion

Dscam

1.47

0,000

0,029

16

Cell adhesion, Nervous system develop ment

Dyrk1a

1.35

0,000

0,003

16

Peptidyl-tyrosine phosphorylation

Entpd3

0.84

0

0,028

9

Nucleoside diphosphate catabolic process

Ets2

1.49

0,000

0,021

16

Regulation of cell cycle

Gin1

1.19

0

0,007

1

DNA recombination

Gng4

0.63

0

0,002

13

Signal transduction

Hfm1

1.29

0

0,016

5

 

Hlcs

1.33

0,000

0,003

16

Protein modification process

Ifngr2

1.35

0,000

0,001

16

 

Itsn1

1.26

0,000

0,003

16

Regulation of Rho protein signal transduction Endocytosis

Kcns2

1.19

0

0,044

15

 

Mrps6

1.43

0,000

0,001

16

Translation

OTTMUSG00000018617

1.65

0

0,001

19

 

Pigp

1.33

0,000

0,022

16

GPI anchor biosynthetic process

Psmg1

1.43

0,000

0,003

16

Cell proliferation

Rcan1

1.37

0,000

0,003

16

Ca2+ mediated signaling

Setd4

1.25

0,000

0,011

16

 

Sfrs15

1.39

0,000

0,029

16

 

Sod1

1.59

0,000

0,001

16

Negative regulation of neuron apoptosis Response to oxidative stress

Sp4

0.62

0

0,001

12

 

Tmem50b

1.42

0,000

0,001

16

 

Ttc3

1.29

0,000

0,036

16

zinc ion binding

Wrb

1.4

0,000

0,001

16

 
  1. 32 genes were found significantly differentially expressed by t-test (p < 0.05) followed by False Discovery Rate controlling procedure of Benjamini and Hochberg (q < 0.05). Among them, 23 are three-copy genes, indicated in bold.
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us