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Table 2 Distribution of the eight gene clusters among S. pneumoniae and other species of Streptococcus

From: Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14

Gene clusters

Strains of S. pneumoniae

Strains of other species (identity)

Lantibiotic biosynthesis proteins

CGSP14, SPnINV200

S. thermophilus CNRZ1066 (70–88%)

Tn3872-like transposon

CGSP14

-

Capsular locus

CGSP14, SP14-BS69, SPnINV200

-

19-kb insertion

CGSP14, SPnINV104B, SPnINV200, G54, TIGR4

-

Possible phage remnant

CGSP14, SP6-BS73, SP11-BS70, SP14-BS69, SP19-BS75, G54

S. pyogenes MGAS6180 (76–88%)

Putative resistance island

CGSP14, SP9-BS68, SP14-BS69, SP19-BS75, SPnINV200

-

Tn2008

CGSP14

-

Cell wall surface anchor protein

CGSP14, TIGR4

-