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Table 3 Frequency of uAUGs and uORFs in alternative and constitutive regions

From: Evolution of alternative and constitutive regions of mammalian 5'UTRs

  Human Mouse
Total uAUGs mapped to genomic 6228 1517
uAUGs mapped to ALT 4948 (79%) 1108 (73%)
uAUGs mapped to CONSTIT 1280 (21%) 409 (27%)
uAUGs included in evolutionary conservation analysis in Human-Macaque and Mouse-Rat orthologs 5608 1518
Total uORFs mapped to genomic 4870 1255
uORFs mapped to ALT 3807 (78%) 906 (72%)
uORFs mapped to CONSTIT 1063 (22%) 349 (28%)
uORFs fully contained within ALT 3042 (80%) 667 (74%)
uORFs fully contained within CONSTIT 901 (85%) 324 (94%)
uORFs included in evolutionary conservation analysis in Human-Macaque and Mouse-Rat orthologs 1988 842
  1. Count of uAUGs (top tier) and uORFs (bottom tier) that map to alternative (ALT) and constitutive (CONSTIT) regions of 5'UTR in human and mouse (percentages in parenthesis).