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Table 3 Frequency of uAUGs and uORFs in alternative and constitutive regions

From: Evolution of alternative and constitutive regions of mammalian 5'UTRs

 

Human

Mouse

Total uAUGs mapped to genomic

6228

1517

uAUGs mapped to ALT

4948 (79%)

1108 (73%)

uAUGs mapped to CONSTIT

1280 (21%)

409 (27%)

uAUGs included in evolutionary conservation analysis in Human-Macaque and Mouse-Rat orthologs

5608

1518

Total uORFs mapped to genomic

4870

1255

uORFs mapped to ALT

3807 (78%)

906 (72%)

uORFs mapped to CONSTIT

1063 (22%)

349 (28%)

uORFs fully contained within ALT

3042 (80%)

667 (74%)

uORFs fully contained within CONSTIT

901 (85%)

324 (94%)

uORFs included in evolutionary conservation analysis in Human-Macaque and Mouse-Rat orthologs

1988

842

  1. Count of uAUGs (top tier) and uORFs (bottom tier) that map to alternative (ALT) and constitutive (CONSTIT) regions of 5'UTR in human and mouse (percentages in parenthesis).