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Table 4 Observed and expected frequency of AUG triplets and shuffled triplets

From: Evolution of alternative and constitutive regions of mammalian 5'UTRs

   Human   Mouse  
   Obs Exp Obs Exp
ATG ALT 10.2 12.9 10.4 13
  CONSTIT 7.9 12.4 8.6 12.7
AGT/GTA/GAT/TAG/TGA ALT 60.9 64.5 65.8 65.0
   (12.1) (12.9) (13.2) (13.0)
  CONSTIT 58.7 62.0 63.7 63.5
   (11.7) (12.4) (12.8) (12.7)
  1. Observed and expected frequencies of AUG triplets (top tier) and shuffled triplets (AGT/GTA/GAT/TAG/TGA) that are permutations of AUG (bottom tier), per 1000 nucleotides in ALT and CONSTIT regions of 5'UTR. The significance of the differences between expected and observed frequencies of uAUG and shuffled triplets was estimated using the χ2 test. All comparisons using the χ2 test are highly significant (P < 10-10) except for two cases in mouse: observed ALT_AGT/GTA/GAT/TAG/TGA versus expected ALT_AGT/GTA/GAT/TAG/TGA (P = 0.41) and observed CONSTIT_AGT/GTA/GAT/TAG/TGA versus expected CONSTIT_AGT/GTA/GAT/TAG/TGA (P = 0.97).